J
Jun Fan
Researcher at Stanford University
Publications - 7
Citations - 3479
Jun Fan is an academic researcher from Stanford University. The author has contributed to research in topics: Chlamydia trachomatis & Genome. The author has an hindex of 5, co-authored 5 publications receiving 3415 citations. Previous affiliations of Jun Fan include University of California, San Francisco.
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Journal ArticleDOI
Genome Sequence of an Obligate Intracellular Pathogen of Humans: Chlamydia trachomatis
Richard S. Stephens,Sue Kalman,Claudia J. Lammel,Jun Fan,Rekha Marathe,L. Aravind,Wayne Mitchell,Lynn Olinger,Roman L. Tatusov,Qixun Zhao,Eugene V. Koonin,Ronald W. Davis +11 more
TL;DR: The phylogenetic mosaic of chlamydial genes, including a large number of genes with phylogenetic origins from eukaryotes, implies a complex evolution for adaptation to obligate intracellular parasitism.
Journal ArticleDOI
A gene map of the human genome
Gregory D. Schuler,Mark S. Boguski,Elizabeth A. Stewart,Lincoln Stein,Gabor Gyapay,Kate Rice,Robert E. White,P. Rodriguez-Tomé,Amita Aggarwal,Eva Bajorek,S. Bentolila,B. B. Birren,Adam Butler,Andrew B. Castle,N. Chiannilkulchai,Angela M. Chu,C M Clee,Sid Cowles,P. J. R. Day,T. Dibling,N. Drouot,Ian Dunham,Simone Duprat,C. East,C A Edwards,Jun Fan,Nicole Y. Fang,Cécile Fizames,Christine Garrett,L. Green,David Hadley,Midori A. Harris,Paul Harrison,Shannon T. Brady,Andrew A. Hicks,E. Holloway,L. Hui,S. Hussain,C. Louis-Dit-Sully,J. Ma,A. MacGilvery,Christopher Mader,A. Maratukulam,Tara C. Matise,K. B. McKusick,Jean Morissette,Andrew J. Mungall,Delphine Muselet,H. C. Nusbaum,David C. Page,Ammon B. Peck,Shanti M. Perkins,Mark Piercy,Fawn Qin,John Quackenbush,S A Ranby,Tim Reif,Steve Rozen,C. Sanders,X. She,James Silva,Donna K. Slonim,Carol Soderlund,W.-L. Sun,P. Tabar,T. Thangarajah,Nathalie Vega-Czarny,Douglas Vollrath,S. Voyticky,T. E. Wilmer,Xiao-Yu Wu,Mark Raymond Adams,Charles Auffray,Nicole A.R. Walter,Rhonda Brandon,Anindya Dehejia,Peter N. Goodfellow,R. Houlgatte,James R. Hudson,Susan E. Ide,K. R. Iorio,Wha‐Young Lee,N. Seki,Takahiro Nagase,K. Ishikawa,N. Nomura,Cheryl Phillips,Mihael H. Polymeropoulos,Mina Sandusky,Karin Schmitt,Richard Berry,K. Swanson,R. Torres,J. C. Venter,James M. Sikela,Jacques S. Beckmann,Jean Weissenbach,Richard M. Myers,David R. Cox,Michael R. James,David Bentley,Panos Deloukas,Eric S. Lander,Thomas J. Hudson,Thomas J. Hudson +104 more
TL;DR: The gene map unifies the existing genetic and physical maps with the nucleotide and protein sequence databases in a fashion that should speed the discovery of genes underlying inherited human disease.
Journal ArticleDOI
Comparative genomes of Chlamydia pneumoniae and C. trachomatis.
Sue Kalman,Wayne Mitchell,Wayne Mitchell,Rekha Marathe,Claudia J. Lammel,Jun Fan,Richard W. Hyman,Lynn Olinger,Lynn Olinger,Jane Grimwood,Ronald W. Davis,Richard S. Stephens,Richard S. Stephens +12 more
TL;DR: Analysis of the C. pneumoniae genome revealed 214 protein-coding sequences not found in C. trachomatis, most without homologues to other known sequences, which will provide an understanding of the common biological processes required for infection and survival in mammalian cells.
Journal ArticleDOI
Antigen conformation dependence of Chlamydia trachomatis infectivity neutralization.
Jun Fan,Richard S. Stephens +1 more
TL;DR: The relative capacity of murine polyvalent sera produced following infection, recovery, and challenge to neutralize infectivity was highly serovar-specific and dependent upon thermolabile antigens.
Journal ArticleDOI
Chlamydial genovar distribution after communitywide antibiotic treatment
Deborah L. Bain,Thomas M. Lietman,Stephanie Rasmussen,Sue Kalman,Jun Fan,Claudia J. Lammel,Jianzhi Zhang,Chandler R. Dawson,Julius Schachter,Richard S. Stephens,Richard S. Stephens +10 more
TL;DR: Major outer membrane protein sequences, determined from Chlamydia-positive eye swab samples collected in 2 Egyptian villages, were used to analyze the epidemiology of trachoma in an endemic setting.