Claudio Santi

TL;DR: The newly approved pharmaceuticals feature several types of aromatic F- and CF3-, aliphatic (CF2) substitution, offering advances in treatment of various diseases, including cancer, HIV, malarial and smallpox infections.

TL;DR: It is shown that selenium-based catalysts can be used conveniently in a series of functional group transformations and can transfer oxygen from environmentally friendly oxidants such as H2O2.

TL;DR: The use of selenating reagents has often been limited by a generally bad reputation surrounding selenium toxicity and its potential impact on the environment as discussed by the authors, however, some aspects that will encourage the reader to discover an unexpected "green side" to this element and the chemistry connected with its organic derivatives.

TL;DR: A series of 2,2'-diselenobisbenzoic scaffold, amino acid, and benzenesulfonamide derivatives are identified as novel HIV retroviral nucleocapsid protein 7 (NCp7) inhibitors and their mechanism of action is based on NCp7 inhibition.

TL;DR: The state of the art of organoselenium compounds as reagents and catalysts for green chemistry has been discussed in this article, providing a comprehensive overview on bioactive organose-lenium compound and their potential therapeutic uses.