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Clay Deming

Researcher at National Institutes of Health

Publications -  15
Citations -  3018

Clay Deming is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Microbiome & Candida auris. The author has an hindex of 9, co-authored 15 publications receiving 2247 citations.

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Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis

TL;DR: Findings reveal linkages between microbial communities and inflammatory diseases such as AD, and demonstrate that as compared with culture-based studies, higher resolution examination of microbiota associated with human disease provides novel insights into global shifts of bacteria relevant to disease progression and treatment.
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Biogeography and individuality shape function in the human skin metagenome

TL;DR: This work developed a relational analysis of bacterial, fungal and viral communities, which showed not only site specificity but also individual signatures, and identified strain-level variation of dominant species as heterogeneous and multiphyletic.
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Staphylococcus aureus and Staphylococcus epidermidis strain diversity underlying pediatric atopic dermatitis

TL;DR: Results highlight that not all Staphylococcus can be considered the same, even at the strain level, when it comes to atopic dermatitis pathogenesis, and Integrating high-resolution sequencing, culturing, and animal models demonstrated how functional differences of staphylitiscal strains may contribute to the complexity of AD disease.
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Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of Bacterial Plasmids Conferring Carbapenem Resistance

TL;DR: This comprehensive survey revealed a vast, unappreciated reservoir of CPOs in wastewater, which was in contrast to the low positivity rate in both the patient population and the patient-accessible environment, and understanding the plasmid ecology of the hospital environment can assist in the design of control strategies to prevent nosocomial infections.
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Diverse Human Skin Fungal Communities in Children Converge in Adulthood

TL;DR: Comparisons of fungal communities of primary clinical samples from healthy children and adults indicate that prepubertal skin is colonized by diverse fungi, whereas adult skin is predominantly obligatory lipophilic Malassezia, suggesting thatFungal communities on skin profoundly shift during puberty.