C
Cora Weigert
Researcher at University of Tübingen
Publications - 134
Citations - 6487
Cora Weigert is an academic researcher from University of Tübingen. The author has contributed to research in topics: Skeletal muscle & Insulin. The author has an hindex of 45, co-authored 122 publications receiving 5667 citations. Previous affiliations of Cora Weigert include Cora & Ludwig Maximilian University of Munich.
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Journal ArticleDOI
Palmitate, but Not Unsaturated Fatty Acids, Induces the Expression of Interleukin-6 in Human Myotubes through Proteasome-dependent Activation of Nuclear Factor-κB
Cora Weigert,Katrin Brodbeck,Harald Staiger,Christiana Kausch,Fausto Machicao,Hans U. Häring,Erwin Schleicher +6 more
TL;DR: IL-6 expression may be modulated by the composition of circulating FFA, e.g. by diet, and that skeletal muscle cells could be target cells for IL-6, which is a major target of impaired insulin action.
Journal ArticleDOI
Role of the hexosamine biosynthetic pathway in diabetic nephropathy.
Erwin Schleicher,Cora Weigert +1 more
TL;DR: Current data indicate that the flux through the hexosamine pathway, regulated by GFAT, may be causally involved in the development of diabetic vascular disease, particularly diabetic nephropathy.
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The impact of insulin resistance on the kidney and vasculature
Ferruh Artunc,Erwin Schleicher,Cora Weigert,Andreas Fritsche,Norbert Stefan,Hans-Ulrich Häring +5 more
TL;DR: Therapeutically, renal and vascular insulin resistance can be improved by an integrated holistic approach aimed at restoring overall insulin sensitivity and improving insulin signalling.
Journal ArticleDOI
Skeletal Muscle as an Endocrine Organ: The Role of Myokines in Exercise Adaptations
Christoph Hoffmann,Cora Weigert +1 more
TL;DR: Muscle-derived regulatory RNAs and metabolites, as well as the design of modified myokines, are promising novel directions for treatment of chronic diseases.
Journal ArticleDOI
Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat
Norbert Stefan,Fausto Machicao,Harald Staiger,Juergen Machann,Fritz Schick,Otto Tschritter,Christian Spieth,Cora Weigert,Andreas Fritsche,Michael Stumvoll,HU Häring +10 more
TL;DR: The present findings suggest that the −8503 G/A SNP in the promoter or the −1927 T/C SNP in intron 1 of ADIPOR1 may affect insulin sensitivity and liver fat in humans.