C
Corine P. Richard
Researcher at University of Texas Southwestern Medical Center
Publications - 6
Citations - 44
Corine P. Richard is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Ghrelin & Internal medicine. The author has an hindex of 1, co-authored 3 publications receiving 4 citations.
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Journal ArticleDOI
LEAP2 deletion in mice enhances ghrelin's actions as an orexigen and growth hormone secretagogue.
Kripa Shankar,Nathan P. Metzger,Omprakash Singh,Bharath K. Mani,Sherri Osborne-Lawrence,Salil Varshney,Deepali Gupta,Sean B. Ogden,Shota Takemi,Corine P. Richard,Karabi Nandy,Chen Liu,Jeffrey M. Zigman +12 more
TL;DR: The first known LEAP2-KO mouse line was generated in this paper, where the metabolic effects of genetic leaper-expressed antimicrobial peptide-2 (LEAP2) deletion were determined.
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Disrupting the ghrelin-growth hormone axis limits ghrelin's orexigenic but not glucoregulatory actions.
Deepali Gupta,Anna M. Patterson,Sherri Osborne-Lawrence,Angie L. Bookout,Salil Varshney,Kripa Shankar,Omprakash Singh,Nathan P. Metzger,Corine P. Richard,Steven C. Wyler,Joel K. Elmquist,Jeffrey M. Zigman +11 more
TL;DR: In this article, the functional significance of acyl-ghrelin's action on GHSR-expressing somatotrophs in mediating GH secretion and several metabolic actions was determined.
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Ghrelin cell-expressed insulin receptors mediate meal- and obesity-induced declines in plasma ghrelin.
Kripa Shankar,Shota Takemi,Deepali Gupta,Salil Varshney,Bharath K. Mani,Sherri Osborne-Lawrence,Nathan P. Metzger,Corine P. Richard,Eric D. Berglund,Jeffrey M. Zigman +9 more
TL;DR: In this article, the impact of insulin, acting via Ghrelin cell-expressed insulin receptors (IRs), to suppress ghrelin secretion was investigated using mice with and without IRs.
Journal ArticleDOI
Effects of thermoneutrality on food intake, body weight, and body composition in a Prader‐Willi syndrome mouse model
Sherri Osborne-Lawrence,Nathan P. Metzger,Corine P. Richard,Salil Varshney,Deepali Gupta,Omprakash Singh,Sean B. Ogden,Kripa Shankar,Subhojit Paul,Jeffrey M. Zigman +9 more
TL;DR: The authors showed that none of several mouse models carrying PWS mutations emulates the entirety of the human PWS phenotype, including hyperphagia plus obesity, in a mouse model.
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Ghrelin does not impact the blunted counterregulatory response to recurrent hypoglycemia in mice
Kripa Shankar,Salil Varshney,Deepali Gupta,Bharath K. Mani,Sherri Osborne-Lawrence,Nathan P. Metzger,Corine P. Richard,Jeffrey M. Zigman +7 more
TL;DR: In this paper , the authors tested the hypothesis that attenuated release of ghrelin both results from HAAF and contributes to hypoglycemia unawareness in patients with diabetes mellitus.