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Cornelis Kluft
Researcher at University of Southern Denmark
Publications - 246
Citations - 8571
Cornelis Kluft is an academic researcher from University of Southern Denmark. The author has contributed to research in topics: Plasminogen activator & Fibrinolysis. The author has an hindex of 46, co-authored 245 publications receiving 8140 citations. Previous affiliations of Cornelis Kluft include Leiden University & Netherlands Organisation for Applied Scientific Research.
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Journal ArticleDOI
Major circadian fluctuations in fibrinolytic factors and possible relevance to time of onset of myocardial infarction, sudden cardiac death and stroke.
Felicita Andreotti,Graham J. Davies,David Hackett,Mohamed I. Khan,Anton C.W. de Bart,Victor R. Aber,Attilio Maseri,Cornelis Kluft +7 more
TL;DR: D markedly reduced fibrinolytic activity during the early morning hours related to increased plasminogen activator inhibition is reported.
Journal ArticleDOI
The postoperative fibrinolytic shutdown: a rapidly reverting acute phase pattern for the fast-acting inhibitor of tissue-type plasminogen activator after trauma
Cornelis Kluft,Jan H. Verheijen,A.F.H. Jie,D. C. Rijken,F. E. Preston,H. M. Sue-Ling,Jørgen Jespersen,A. O. Aasen +7 more
TL;DR: It is concluded that t-PA inhibition shows the most rapidly changing pattern observed so far in response to trauma, and the postoperative fibrinolytic shutdown in blood fibrinogen and C-reactive protein can be ascribed to a primary increase in t- PA inhibitor levels.
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Polymorphisms in the Coagulation Factor VII Gene and the Risk of Myocardial Infarction
Licia Iacoviello,Augusto Di Castelnuovo,Peter de Knijff,Andria D'Orazio,C. Amore,Rosa Arboretti,Cornelis Kluft,Maria Benedetta Donati +7 more
TL;DR: The findings suggest that certain polymorphisms of the factor VII gene may influence the risk of myocardial infarction and it is possible that this effect may be mediated by alterations in factor VII levels.
Journal ArticleDOI
Association of depressive disorders, depression characteristics and antidepressant medication with inflammation
Nicole Vogelzangs,Hester E. Duivis,Aartjan T.F. Beekman,Cornelis Kluft,Jacoline Neuteboom,Witte J.G. Hoogendijk,Johannes H. Smit,de Peter Jonge,Brenda W.J.H. Penninx,Brenda W.J.H. Penninx,Brenda W.J.H. Penninx +10 more
TL;DR: Elevated inflammation was confirmed in depressed men, especially those with a late-onset depression, and specific antidepressants may differ in their effects on inflammation.
Journal ArticleDOI
Effect of Moderate Alcohol Consumption on Adiponectin, Tumor Necrosis Factor-α, and Insulin Sensitivity
Aafje Sierksma,Hamina J. Patel,Noriyuki Ouchi,Shinji Kihara,Tohru Funahashi,Robert J. Heine,Diederick E. Grobbee,Cornelis Kluft,H.F.J. Hendriks +8 more
TL;DR: Moderate alcohol consumption improved insulin sensitivity in relatively insulin-resistant middle-aged men, an effect that may be mediated through alcohol-induced increases in adiponectin.