C
Corrine R. Davis
Researcher at Stanford University
Publications - 12
Citations - 6090
Corrine R. Davis is an academic researcher from Stanford University. The author has contributed to research in topics: Carbon nanotubes in medicine & Perfusion. The author has an hindex of 12, co-authored 12 publications receiving 5712 citations.
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Journal ArticleDOI
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways.
Dirk Grimm,Konrad L. Streetz,Konrad L. Streetz,Catherine L. Jopling,Theresa A. Storm,Kusum Pandey,Corrine R. Davis,Patricia L. Marion,Felix H. Salazar,Mark A. Kay +9 more
TL;DR: The risk of oversaturating endogenous small RNA pathways can be minimized by optimizing shRNA dose and sequence, as exemplified here by the report of persistent and therapeutic RNAi against human hepatitis B virus in vivo.
Journal ArticleDOI
Drug delivery with carbon nanotubes for in vivo cancer treatment.
TL;DR: In vivo SWNT drug delivery for tumor suppression in mice shows nanotube drug delivery is promising for high treatment efficacy and minimum side effects for future cancer therapy with low drug doses.
Journal ArticleDOI
Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy
TL;DR: Functionalization of SWNTs by branched polyethylene-glycol (PEG) chains was developed, enabling thus far the longest SWNT blood circulation up to 1 day, relatively low uptake in the reticuloendothelial system (RES), and near-complete clearance from the main organs in ≈2 months.
Posted ContentDOI
Drug delivery with carbon nanotubes for in vivo cancer treatment
TL;DR: In-vivo nanotube drug delivery for tumor suppression in mice shows promise for high treatment efficacy and minimum side effects for future cancer therapy with low drug doses.
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A pilot toxicology study of single-walled carbon nanotubes in a small sample of mice
Meike L. Schipper,Nozomi Nakayama-Ratchford,Corrine R. Davis,Nadine Wong Shi Kam,Pauline Chu,Zhuang Liu,Xiaoming Sun,Hongjie Dai,Sanjiv S. Gambhir +8 more
TL;DR: Histology and Raman microscopic mapping demonstrate that functionalized single-walled carbon nanotubes persisted within liver and spleen macrophages for 4 months without apparent toxicity, and results encourage further confirmation studies with larger groups of animals.