C
Corwin Q. Edwards
Researcher at University of Utah
Publications - 99
Citations - 6010
Corwin Q. Edwards is an academic researcher from University of Utah. The author has contributed to research in topics: Hemochromatosis & Hereditary hemochromatosis. The author has an hindex of 40, co-authored 98 publications receiving 5906 citations. Previous affiliations of Corwin Q. Edwards include Johns Hopkins University School of Medicine & Duke University.
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Journal ArticleDOI
Prevalence of Hemochromatosis among 11,065 Presumably Healthy Blood Donors
Corwin Q. Edwards,Linda M. Griffen,David E. Goldgar,Charles Drummond,Mark H. Skolnick,James P. Kushner +5 more
TL;DR: The value of population screening is demonstrated in these studies by the detection of homozygotes before clinical manifestations of hemochromatosis occur, and the efficacy of transferrin saturation as a screening tool for hemochROMatosis is determined.
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Practice guideline development task force of the College of American Pathologists. Hereditary hemochromatosis.
TL;DR: Systematic screening for hemochromatosis is warranted for all persons over the age of 20 years, and the practice guideline provides a diagnostic algorithm for cases in which the serum transferrin saturation is 60% or greater.
Journal ArticleDOI
Clinical and biochemical abnormalities in people heterozygous for hemochromatosis.
TL;DR: The phenotype of persons heterozygous for hemochromatosis differs from that of normal subjects, but complications due to iron overload alone in these heterozygotes are extremely rare.
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Iron overload in Africa: Interaction between a gene and dietary iron content
Victor R. Gordeuk,Mukiibi Jm,Sandra J. Hasstedt,Wade S. Samowitz,Corwin Q. Edwards,George L. West,Solomon Ndambire,Jean Emmanual,Neal Nkanza,Zivanai Chapanduka,Maurice Randall,Paul Boone,Paula J. Romano,R. W. Martell,Toyoko S. Yamashita,Paul Effler,Gary M. Brittenham +16 more
TL;DR: Iron overload in Africa may be caused by an interaction between the amount of dietary iron and a gene distinct from any HLA-linked gene.
Journal ArticleDOI
Hereditary hemochromatosis. Phenotypic expression of the disease.
G E Cartwright,Corwin Q. Edwards,K Kravitz,Mark H. Skolnick,D B Amos,A. H. Johnson,L Buskjaer +6 more
TL;DR: In heterozygotes over 20 years of age, there was an intermediate increase in transferrin saturation and a limited increase in hepatic iron but no clinical manifestations, and all measurements of iron status were increased in abnormal homozygotes.