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Craig A. Hutton
Researcher at University of Melbourne
Publications - 143
Citations - 3064
Craig A. Hutton is an academic researcher from University of Melbourne. The author has contributed to research in topics: Dihydrodipicolinate synthase & Amino acid. The author has an hindex of 34, co-authored 139 publications receiving 2668 citations. Previous affiliations of Craig A. Hutton include University of California, Berkeley & University of Adelaide.
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Journal ArticleDOI
Inhibition of lysine biosynthesis: an evolving antibiotic strategy
TL;DR: Recent advances in the validation of antibiotic targets, studies of the enzymes of the lysine biosynthetic pathway and development of inhibitors of these enzymes are reviewed.
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Deprotection of pinacolyl boronate esters via hydrolysis of intermediate potassium trifluoroborates
TL;DR: An efficient two-step procedure for the deprotection of pinacolyl organoboronate esters is described in this article, where the trifluoroborates with either inorganic base or trimethylsilyl chloride and water are treated.
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Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis.
Marie-Julie Nokin,Florence Durieux,Paul Peixoto,Barbara Chiavarina,Olivier Peulen,Arnaud Blomme,Andrei Turtoi,Brunella Costanza,Nicolas Smargiasso,Dominique Baiwir,Jean L.J.M. Scheijen,Casper G. Schalkwijk,Justine Leenders,Pascal de Tullio,Elettra Bianchi,Marc Thiry,Koji Uchida,David Spiegel,James R. Cochrane,Craig A. Hutton,Edwin De Pauw,Philippe Delvenne,Dominique Belpomme,Vincent Castronovo,Akeila Bellahcene +24 more
TL;DR: Findings reinforce the cumulative evidence pointing to hyperglycemia as a risk factor for cancer incidence and bring renewed interest in MG scavengers for cancer treatment.
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Inhibitors of Lysine Biosynthesis as Antibacterial Agents
TL;DR: Recent studies of the enzymes of the lysine biosynthetic pathway, development of inhibitors and investigations of their antibacterial properties are discussed.
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Oligomers, fact or artefact? SDS-PAGE induces dimerization of β-amyloid in human brain samples
Andrew D Watt,Keyla Perez,Alan Rembach,Nicki A. Sherrat,Lin Wai Hung,Timothy Johanssen,Catriona McLean,Woan Mei Kok,Craig A. Hutton,Michelle T. Fodero-Tavoletti,Colin L. Masters,Victor L. Villemagne,Kevin J. Barnham +12 more
TL;DR: The findings that SDS promotes Aβ dimerization have significant implications for the putative role of low-order oligomers in AD pathogenesis and draw into question the utility of oligomeric Aβ as a therapeutic target.