A
Andrei Turtoi
Researcher at French Institute of Health and Medical Research
Publications - 77
Citations - 1967
Andrei Turtoi is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Cancer & Stromal cell. The author has an hindex of 25, co-authored 67 publications receiving 1472 citations. Previous affiliations of Andrei Turtoi include Gunma University & University of Liège.
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Journal ArticleDOI
Versican overexpression in human breast cancer lesions: known and new isoforms for stromal tumor targeting.
Philippe Kischel,David Waltregny,Bruno Dumont,Andrei Turtoi,Yannick Greffe,Stéphanie Kirsch,Edwin De Pauw,Vincenzo Castronovo +7 more
TL;DR: This study provides for the first time a comprehensive mRNA and protein analysis of versican isoforms expression in human breast tissues, and offers insights into which therapeutic strategy would be best suited to target versican inhuman breast cancer lesions.
Journal ArticleDOI
Stromal Modulators of TGF-β in Cancer
Brunella Costanza,Ijeoma Adaku Umelo,Justine Bellier,Vincent Castronovo,Andrei Turtoi,Andrei Turtoi +5 more
TL;DR: The present review highlights the present understanding of how stroma modulates TGF-β activity in human cancers and highlights the need to understand the complex interplay between the T GF-β signaling network and these stromal proteins.
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Identification of novel accessible proteins bearing diagnostic and therapeutic potential in human pancreatic ductal adenocarcinoma.
Andrei Turtoi,Davide Musmeci,Davide Musmeci,Ying Hong Wang,Bruno Dumont,Joan Somja,Generoso Bevilacqua,Edwin De Pauw,Philippe Delvenne,Vincenzo Castronovo +9 more
TL;DR: TGFBI, LTBP2, and ASPN are novel, overexpressed, and potentially accessible proteins in human PDAC, which bear the potential to be of clinical value for diagnostic and therapeutic applications and merit further studies using in vivo models.
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Asporin Is a Fibroblast-Derived TGF-β1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer.
Pamela Maris,Arnaud Blomme,Ana Palacios,Brunella Costanza,Akeila Bellahcene,Elettra Bianchi,Stéphanie Gofflot,Pierre Drion,Giovanna Elvi Trombino,Emmanuel Di Valentin,P. Cusumano,Sylvie Maweja,Guy Jerusalem,Philippe Delvenne,Eric Lifrange,Vincent Castronovo,Andrei Turtoi +16 more
TL;DR: The data show that asporin is a stroma-derived inhibitor of TGF-β1 and a tumor suppressor in breast cancer.
Journal ArticleDOI
Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis.
Marie-Julie Nokin,Florence Durieux,Paul Peixoto,Barbara Chiavarina,Olivier Peulen,Arnaud Blomme,Andrei Turtoi,Brunella Costanza,Nicolas Smargiasso,Dominique Baiwir,Jean L.J.M. Scheijen,Casper G. Schalkwijk,Justine Leenders,Pascal de Tullio,Elettra Bianchi,Marc Thiry,Koji Uchida,David Spiegel,James R. Cochrane,Craig A. Hutton,Edwin De Pauw,Philippe Delvenne,Dominique Belpomme,Vincent Castronovo,Akeila Bellahcene +24 more
TL;DR: Findings reinforce the cumulative evidence pointing to hyperglycemia as a risk factor for cancer incidence and bring renewed interest in MG scavengers for cancer treatment.