C
Cristian Vilos
Researcher at University of Santiago, Chile
Publications - 47
Citations - 2110
Cristian Vilos is an academic researcher from University of Santiago, Chile. The author has contributed to research in topics: Drug delivery & Medicine. The author has an hindex of 17, co-authored 44 publications receiving 1609 citations. Previous affiliations of Cristian Vilos include Brigham and Women's Hospital & University of Talca.
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Journal ArticleDOI
Insight into nanoparticle cellular uptake and intracellular targeting
Basit Yameen,Won Il Choi,Cristian Vilos,Archana Swami,Jinjun Shi,Omid C. Farokhzad,Omid C. Farokhzad +6 more
TL;DR: An account of ligand-targeted nanoparticles for receptor-mediated cellular internalization as a strategy for modulating the cellular uptake of nanoparticles is presented and prospects, potential, and concrete expectations from the field of targeted nanomedicines and strategies to meet those expectations are provided.
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Targeted Interleukin-10 Nanotherapeutics Developed with a Microfluidic Chip Enhance Resolution of Inflammation in Advanced Atherosclerosis
Nazila Kamaly,Gabrielle Fredman,Jhalique Jane R. Fojas,Manikandan Subramanian,Won Ii Choi,Katherine Zepeda,Cristian Vilos,Mi Kyung Yu,Suresh Gadde,Jun Wu,Jaclyn Milton,Renata Carvalho Leitao,Livia Rosa Fernandes,Moaraj Hasan,Huayi Gao,Vance Nguyen,Jordan Harris,Ira Tabas,Omid C. Farokhzad,Omid C. Farokhzad +19 more
TL;DR: The development and efficacy investigations of controlled-release polymeric nanoparticles incorporating the anti-inflammatory cytokine interleukin 10 (IL-10) for targeted delivery to atherosclerotic plaques are presented.
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Differentially charged hollow core/shell lipid-polymer-lipid hybrid nanoparticles for small interfering RNA delivery.
Jinjun Shi,Zeyu Xiao,Zeyu Xiao,Alexander R. Votruba,Cristian Vilos,Omid C. Farokhzad,Omid C. Farokhzad +6 more
TL;DR: These delivery vehicles are also expected to improve the pharmacological properties of siRNA by reducing its susceptibility to serum nucleases, renal filtration, and uptake by the mononuclear phagocyte system.
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Role of Oxidative Stress as Key Regulator of Muscle Wasting during Cachexia.
Johanna Abrigo,Alvaro A. Elorza,Claudia A. Riedel,Claudia A. Riedel,Cristian Vilos,Felipe Simon,Felipe Simon,Daniel Cabrera,Lisbell D. Estrada,Claudio Cabello-Verrugio,Claudio Cabello-Verrugio +10 more
TL;DR: The importance of oxidative stress in skeletal muscles, its sources, and how it can regulate protein synthesis/degradation imbalance, autophagy deregulation, increased myonuclear apoptosis, and mitochondrial dysfunction involved in cachexia are described.
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Targeted nanoparticles for colorectal cancer.
Bruno A. Cisterna,Nazila Kamaly,Won-Il Choi,Ali Tavakkoli,Omid C. Farokhzad,Omid C. Farokhzad,Cristian Vilos,Cristian Vilos +7 more
TL;DR: Recent advances in targeted nanoparticles against CRC are presented and the promising use of ligands and cellular targets in potential strategies for the treatment of CRCs are discussed.