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Cyril Zipfel

Researcher at University of Zurich

Publications -  208
Citations -  27972

Cyril Zipfel is an academic researcher from University of Zurich. The author has contributed to research in topics: Arabidopsis & Pattern recognition receptor. The author has an hindex of 69, co-authored 185 publications receiving 22688 citations. Previous affiliations of Cyril Zipfel include Friedrich Miescher Institute for Biomedical Research & University of Basel.

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Perception of the bacterial PAMP EF-Tu by the receptor EFR restricts Agrobacterium-mediated transformation.

TL;DR: It is shown that flagellin and EF-Tu activate a common set of signaling events and defense responses but without clear synergistic effects, and that plant defense responses induced by PAMPs such as EF- Tu reduce transformation by Agrobacterium.
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A flagellin-induced complex of the receptor FLS2 and BAK1 initiates plant defence

TL;DR: BAK1 is shown to have a functional role in PRR-dependent signalling, which initiates innate immunity, and evidence is provided that FLS2 and BAK1 form a complex in vivo, in a specific ligand-dependent manner, within the first minutes of stimulation with flagellin.
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Bacterial disease resistance in Arabidopsis through flagellin perception.

TL;DR: It is shown that treatment of plants with flg22, a peptide representing the elicitor-active epitope of flagellin, induces the expression of numerous defence-related genes and triggers resistance to pathogenic bacteria in wild-type plants, but not in plants carrying mutations in the flageLLin receptor gene FLS2.
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The N Terminus of Bacterial Elongation Factor Tu Elicits Innate Immunity in Arabidopsis Plants

TL;DR: It is shown that elongation factor Tu, the most abundant bacterial protein, acts as a PAMP in Arabidopsis thaliana and other Brassicaceae, and an N-acetylated peptide comprising the first 18 amino acids, termed elf18, is fully active as inducer of defense responses.
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Regulation of pattern recognition receptor signalling in plants.

TL;DR: The mechanisms that fine-tune immune signalling to maintain immune homeostasis are described and how the innate ability of plant cells to monitor the integrity of key immune components can lead to autoimmune phenotypes following genetic or pathogen-induced perturbations of these components are discussed.