D
D. Allen
Researcher at Beth Israel Deaconess Medical Center
Publications - 2
Citations - 903
D. Allen is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: X-linked lymphoproliferative disease & Co-receptor. The author has an hindex of 1, co-authored 2 publications receiving 881 citations.
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The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM
Joan Sayós,Chengbin Wu,Massimo Morra,Ninghai Wang,X. Zhang,D. Allen,S. van Schaik,Luigi D. Notarangelo,Raif S. Geha,Maria Grazia Roncarolo,Hans C. Oettgen,J. E. De Vries,Gregorio Aversa,Cox Terhorst +13 more
TL;DR: It is shown that a T-cell-specific, SLAM-associated protein (SAP), which contains an SH2 domain and a short tail, acts as an inhibitor by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region.
Journal Article
Pillars Article: The X-Linked Lymphoproliferative Disease Gene Product SAP Regulates Signals Induced through the Co-Receptor SLAM. Nature. 1998. 395: 462–469
Joan Sayós,Chengbin Wu,Massimo Morra,Ninghai Wang,XiaoLi Zhang,D. Allen,S. van Schaik,Lucia Dora Notarangelo,Raif S. Geha,Maria Grazia Roncarolo,Hans C. Oettgen,J E de Vries,G Aversa,Cox Terhorst +13 more