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D. Mark Pritchard
Researcher at University of Liverpool
Publications - 98
Citations - 4078
D. Mark Pritchard is an academic researcher from University of Liverpool. The author has contributed to research in topics: Gastrin & Helicobacter pylori. The author has an hindex of 32, co-authored 95 publications receiving 3409 citations. Previous affiliations of D. Mark Pritchard include University of Manchester & Royal Liverpool and Broadgreen University Hospital NHS Trust.
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Journal ArticleDOI
The intestinal epithelial stem cell: the mucosal governor
TL;DR: The various growth and matrix factors and genes which may control these processes, and be important for stem cell function, are discussed along with their carcinogenic and clinical implications.
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British Society of Gastroenterology guidelines on the diagnosis and management of patients at risk of gastric adenocarcinoma
Matthew R. Banks,David Graham,Marnix Jansen,Takuji Gotoda,Sergio Coda,Massimiliano di Pietro,Noriya Uedo,Pradeep Bhandari,D. Mark Pritchard,Ernst J. Kuipers,Manuel Rodriguez-Justo,Marco Novelli,Krish Ragunath,Neil A. Shepherd,Mário Dinis-Ribeiro +14 more
TL;DR: There is insufficient evidence to support screening in a low-risk population (undergoing routine diagnostic oesophagogastroduodenoscopy) such as the UK, but endoscopic surveillance every 3 years should be offered to patients with extensive GA or GIM.
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The management of gastric polyps
TL;DR: This work has shown that sessile or pedunculated lesions that originate in the gastric epithelium or submucosa and protrude into the stomach lumen and may also indicate an increased risk of intestinal or extra-intestinal malignancy.
Journal ArticleDOI
Characterization of epithelial cell shedding from human small intestine
Tim Bullen,Sharon Forrest,Fiona Campbell,Andrew Dodson,Michael J Hershman,D. Mark Pritchard,Jerrold R. Turner,Marshall H. Montrose,Alastair J.M. Watson +8 more
TL;DR: Cell shedding is associated with apoptosis though it remains unclear whether apoptosis initiates shedding and it is also associated with phosphorylation of MLCs; a process associated previously with wound healing.
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Gastrin induces proliferation in Barrett's metaplasia through activation of the CCK2 receptor
Chris Haigh,Stephen Attwood,David G. Thompson,Janusz Jankowski,Christopher M. Kirton,D. Mark Pritchard,Andrea Varro,Rod Dimaline +7 more
TL;DR: Gastrin induces proliferation via the CCK(2) receptor in Barrett's mucosa and may have implications for the management of patients with Barrett's esophagus in whom gastrin is elevated by acid-suppression therapy.