H
Harald Stein
Researcher at Free University of Berlin
Publications - 267
Citations - 18977
Harald Stein is an academic researcher from Free University of Berlin. The author has contributed to research in topics: Lymphoma & Antigen. The author has an hindex of 77, co-authored 267 publications receiving 18495 citations. Previous affiliations of Harald Stein include Harvard University & Charité.
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Journal ArticleDOI
CD30(+) anaplastic large cell lymphoma: a review of its histopathologic, genetic, and clinical features.
Harald Stein,Hans-Dieter Foss,Horst Dürkop,Theresa Marafioti,Georges Delsol,Karen Pulford,Stefano Pileri,Brunangelo Falini +7 more
TL;DR: Recent immunohistologic studies suggest that ALCLs Hodgkin-like represent either cases of tumor cell-rich classic Hodgkin disease or (less commonly) ALK(+) ALCL orALK(-) ALCL, both of which have an unfavorable prognosis.
Journal ArticleDOI
Plasmablastic Lymphomas of the Oral Cavity: A New Entity Associated With the Human Immunodeficiency Virus Infection
Henri Jacques Delecluse,Ioannis Anagnostopoulos,Ioannis Anagnostopoulos,Friederike Dallenbach,Friederike Dallenbach,Michael Hummel,Michael Hummel,Teresa Marafioti,Teresa Marafioti,U. Schneider,U. Schneider,D. Huhn,D. Huhn,A. Schmidt-Westhausen,A. Schmidt-Westhausen,Peter A. Reichart,Peter A. Reichart,Ulrich Gross,Ulrich Gross,Harald Stein,Harald Stein +20 more
TL;DR: A series of 16 highly malignant diffuse large B-cell lymphomas of the oral cavity with unique immunohistologic features that developed in human immunodeficiency virus-positive patients are reported, and it is proposed to name these tumors plasmablastic lymphomas, in accordance with their morphologic and immunohISTologic features.
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Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease.
TL;DR: CDNAs coding for the HD characteristic antigen CD30 were cloned from expression libraries of the human HUT-102 cell line using the monoclonal antibodies Ki-1 and Ber-H2 and proved to be homologous to members of the nerve growth factor receptor superfamily.
Journal ArticleDOI
Hodgkin and Reed-Sternberg cells represent an expansion of a single clone originating from a germinal center B-cell with functional immunoglobulin gene rearrangements but defective immunoglobulin transcription
Theresa Marafioti,Michael Hummel,Michael Hummel,Hans-Dieter Foss,Hans-Dieter Foss,Helmut Laumen,Helmut Laumen,Korbjuhn P,Korbjuhn P,Ioannis Anagnostopoulos,Ioannis Anagnostopoulos,Hetty Lammert,Hetty Lammert,Gudrun Demel,Gudrun Demel,Jan Theil,Jan Theil,Thomas Wirth,Thomas Wirth,Harald Stein,Harald Stein +20 more
TL;DR: In this paper, a single-cell study was performed on 25 patients with Hodgkin and Reed-Sternberg (HRS) disease, with and without Epstein-Barr virus infection, for the presence of gene rearrangements.
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Demonstration of monoclonal EBV genomes in Hodgkin's disease and Ki-1-positive anaplastic large cell lymphoma by combined Southern blot and in situ hybridization.
TL;DR: In situ hybridization revealed that in two HD cases, the EBV infected cells had the distinct morphology of Hodgkin and Reed-Sternberg cells, thus suggesting a direct pathoetiological relationship between EBV and some cases of HD.