D
Daisuke Iitaka
Researcher at Kyoto Prefectural University of Medicine
Publications - 21
Citations - 571
Daisuke Iitaka is an academic researcher from Kyoto Prefectural University of Medicine. The author has contributed to research in topics: Cancer & Cancer cell. The author has an hindex of 12, co-authored 19 publications receiving 520 citations. Previous affiliations of Daisuke Iitaka include University Health Network.
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Journal ArticleDOI
Circulating microRNAs in plasma of patients with oesophageal squamous cell carcinoma
Shuhei Komatsu,Daisuke Ichikawa,Hideyuki Takeshita,Masahiro Tsujiura,R Morimura,H Nagata,Toshiyuki Kosuga,Daisuke Iitaka,Hirotaka Konishi,Atsushi Shiozaki,Hitoshi Fujiwara,Kazuma Okamoto,Eigo Otsuji +12 more
TL;DR: Detection of circulating miRNAs might provide new complementary tumour markers for ESCC by monitoring tumour dynamics through plasma miRNA assays.
Journal ArticleDOI
XB130, a new adaptor protein, regulates expression of tumor suppressive microRNAs in cancer cells.
Hiroki Takeshita,Hiroki Takeshita,Atsushi Shiozaki,Xiao-Hui Bai,Daisuke Iitaka,Daisuke Iitaka,Hyunhee Kim,Burton B. Yang,Shaf Keshavjee,Shaf Keshavjee,Mingyao Liu,Mingyao Liu +11 more
TL;DR: The results suggest that XB130 could promote growth of cancer cells by regulating expression of tumor suppressive miRNAs and their targeted genes.
Journal ArticleDOI
XB130 Mediates Cancer Cell Proliferation and Survival through Multiple Signaling Events Downstream of Akt
Atsushi Shiozaki,Grace Shen-Tu,Xiao-Hui Bai,Daisuke Iitaka,Valentina De Falco,Massimo Santoro,Shaf Keshavjee,Shaf Keshavjee,Mingyao Liu,Mingyao Liu +9 more
TL;DR: Results indicate that XB130 is a substrate of multiple protein tyrosine kinases, and it can regulate cell proliferation and survival through modulating selected down-stream signals of PI3K/Akt pathway.
Journal ArticleDOI
xCT, component of cysteine/glutamate transporter, as an independent prognostic factor in human esophageal squamous cell carcinoma
Atsushi Shiozaki,Daisuke Iitaka,Daisuke Ichikawa,Shingo Nakashima,Hitoshi Fujiwara,Kazuma Okamoto,Takeshi Kubota,Shuhei Komatsu,Toshiyuki Kosuga,Hiroki Takeshita,Hiroki Shimizu,Yoshito Nako,Hisami Sasagawa,Mitsuo Kishimoto,Eigo Otsuji +14 more
TL;DR: Immunohistochemical staining showed that xCT is mainly found in the nuclei of carcinoma cells, and that its expression is an independent prognostic factor, suggesting that the expression of xCT in ESCC cells might affect the G1/S checkpoint and impact on the prognosis of ESCC patients.
Journal ArticleDOI
Claudin 1 mediates tumor necrosis factor alpha-induced cell migration in human gastric cancer cells
Atsushi Shiozaki,Hiroki Shimizu,Daisuke Ichikawa,Hirotaka Konishi,Shuhei Komatsu,Takeshi Kubota,Hitoshi Fujiwara,Kazuma Okamoto,Daisuke Iitaka,Shingo Nakashima,Yoshito Nako,Mingyao Liu,Eigo Otsuji +12 more
TL;DR: Results suggest that claudin 1 is an important messenger that regulates TNF-α-induced gene expression and migration in gastric cancer cells.