D
Dan Sørensen
Publications - 1
Citations - 121
Dan Sørensen is an academic researcher. The author has contributed to research in topics: Cell culture. The author has an hindex of 1, co-authored 1 publications receiving 105 citations.
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Development of a liver-targeted stearoyl-CoA desaturase (SCD) inhibitor (MK-8245) to establish a therapeutic window for the treatment of diabetes and dyslipidemia.
Renata Oballa,Liette Belair,W. Cameron Black,Kelly Bleasby,Chi-Chung Chan,Carole Desroches,Xiaobing Du,R. Gordon,Jocelyne Guay,Sébastien Guiral,Michael J. Hafey,Emelie Hamelin,Zheng Huang,Brian P. Kennedy,Nicolas Lachance,Chun Sing Li,Joseph A. Mancini,Denis Normandin,Alessandro Pocai,David A. Powell,Yeeman K. Ramtohul,Kathryn Skorey,Dan Sørensen,Wayne Sturkenboom,Angela Styhler,Deena Waddleton,Hao Wang,Simon Wong,Lijing Xu,Lei Zhang +29 more
TL;DR: The discovery of MK-8245 is found, a potent, liver-targeted SCD inhibitor with preclinical antidiabetic and antidyslipidemic efficacy with a significantly improved therapeutic window.