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Daniel B. Werz
Researcher at Braunschweig University of Technology
Publications - 279
Citations - 10770
Daniel B. Werz is an academic researcher from Braunschweig University of Technology. The author has contributed to research in topics: Catalysis & Chemistry. The author has an hindex of 52, co-authored 264 publications receiving 8884 citations. Previous affiliations of Daniel B. Werz include University of Göttingen & École Polytechnique Fédérale de Lausanne.
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A new golden age for donor-acceptor cyclopropanes.
TL;DR: This Review highlights the appropriate tools for successfully employing donor-acceptor cyclopropanes in ring-opening reactions, cycloadditions, and rearrangements.
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Synthesis and medical applications of oligosaccharides
TL;DR: Synthetic tools and high-throughput experiments such as carbohydrate arrays are beginning to affect biological research, and are being applied to the development of carbohydrate-based diagnostics, vaccines and therapeutics.
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Theoretical Investigations on Chalcogen−Chalcogen Interactions: What Makes These Nonbonded Interactions Bonding?
TL;DR: A detailed analysis based on symmetry adapted perturbation theory (SAPT) reveals that induction and dispersion forces contribute to the bonding in each case, and the interaction in the dimers 1-3 is mainly due to weak hydrogen bonding between methyl groups and chalcogen centers.
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Exploring the Structural Diversity of Mammalian Carbohydrates (“Glycospace”) by Statistical Databank Analysis
Daniel B. Werz,Rene Ranzinger,Stephan Herget,Alexander Adibekian,Claus-Wilhelm von der Lieth,Peter H. Seeberger +5 more
TL;DR: The diversity of three major classes of mammalian carbohydrates, mainly glycolipids and O- and N-linked glycans, deposited in the databank GLYCOSCIENCES.de was subjected to statistical analyses and a potential set of building blocks for oligosaccharide assembly is presented.
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Automated synthesis of oligosaccharides as a basis for drug discovery
TL;DR: Particular focus will be placed on the development of carbohydrate-based vaccines, defined heparin oligosaccharides and aminoglycosides that have recently begun to affect drug discovery.