D
Daniel Figeys
Researcher at University of Ottawa
Publications - 285
Citations - 16979
Daniel Figeys is an academic researcher from University of Ottawa. The author has contributed to research in topics: Microbiome & Metaproteomics. The author has an hindex of 60, co-authored 266 publications receiving 15040 citations. Previous affiliations of Daniel Figeys include Beihang University & Temple University.
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Journal ArticleDOI
Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry
Yuen Ho,Albrecht Gruhler,Adrian Heilbut,Gary D. Bader,Gary D. Bader,Lynda Moore,Sally-Lin Adams,Anna Millar,Paul J. Taylor,Keiryn L. Bennett,Kelly Boutilier,Lingyun Yang,Cheryl Wolting,Ian Donaldson,Søren Schandorff,Juanita Shewnarane,Mai Vo,Joanne Taggart,Marilyn Goudreault,Brenda Muskat,Cris Alfarano,Danielle Dewar,Zhen Lin,Katerina Michalickova,Katerina Michalickova,Andrew Willems,Andrew Willems,Holly Sassi,Peter A Nielsen,Karina Juhl Rasmussen,Jens R. Andersen,Lene E. Johansen,Lykke Haastrup Hansen,Hans Jespersen,Alexandre V. Podtelejnikov,Eva Nielsen,Janne S. Crawford,Vibeke Poulsen,Birgitte D Sørensen,Jesper Matthiesen,Ronald C. Hendrickson,Frank Gleeson,Tony Pawson,Tony Pawson,Michael Moran,Daniel Durocher,Daniel Durocher,Matthias Mann,Christopher W. V. Hogue,Christopher W. V. Hogue,Daniel Figeys,Mike Tyers,Mike Tyers +52 more
TL;DR: Comparison of the HMS-PCI data set with interactions reported in the literature revealed an average threefold higher success rate in detection of known complexes compared with large-scale two-hybrid studies.
Journal ArticleDOI
Large‐scale mapping of human protein–protein interactions by mass spectrometry
Rob M. Ewing,Peter Chu,Fred Elisma,Hongyan Li,Paul J. Taylor,Shane Climie,Linda McBroom-Cerajewski,Mark D. Robinson,Liam O'Connor,Michael Li,Rod Taylor,Moyez Dharsee,Yuen Ho,Adrian Heilbut,Lynda Moore,Shudong Zhang,Olga Ornatsky,Yury V. Bukhman,Martin Ethier,Yinglun Sheng,Julian Vasilescu,Mohamed Abu-Farha,Jean-Philippe Lambert,Henry S. Duewel,Ian I. Stewart,Bonnie Kuehl,Kelly Hogue,Karen Colwill,Katharine Gladwish,Brenda Muskat,Robert Kinach,Sally Lin Adams,Michael Moran,Gregg B. Morin,Thodoros Topaloglou,Daniel Figeys +35 more
TL;DR: In‐depth mining of the data set shows that it represents a valuable source of novel protein–protein interactions with relevance to human diseases, and via the preliminary analysis, many novel protein interactions and pathway associations are reported.
Journal ArticleDOI
Lab-on-a-Chip: A Revolution in Biological and Medical Sciences.
Daniel Figeys,Devanand M. Pinto +1 more
TL;DR: A look at some of the basic concepts and novel components used to construct prototype devices in the construction of prototype devices.
Journal ArticleDOI
Identification of flow-dependent endothelial nitric-oxide synthase phosphorylation sites by mass spectrometry and regulation of phosphorylation and nitric oxide production by the phosphatidylinositol 3-kinase inhibitor LY294002.
Byron Gallis,Garry L. Corthals,David R. Goodlett,Hiroto Ueba,Francis Kim,Steven R. Presnell,Daniel Figeys,David G. Harrison,Bradford C. Berk,Ruedi Aebersold,Marshall A. Corson +10 more
TL;DR: It is demonstrated that LY294002, an inhibitor of the upstream activator of PKB, phosphatidylinositol 3-kinase, inhibited flow-induced eNOS phosphorylation by 97% and NO production by 68%.
Journal ArticleDOI
18O labeling: a tool for proteomics.
TL;DR: The evaluation of the relative Ziptip efficiency indicated a loss in sample recovery as the peptide concentration was reduced using normal conditions, suggesting that there is a limit below which there are diminishing returns.