J
Julian Vasilescu
Researcher at University of Ottawa
Publications - 13
Citations - 1638
Julian Vasilescu is an academic researcher from University of Ottawa. The author has contributed to research in topics: Proteomics & Protein–protein interaction prediction. The author has an hindex of 11, co-authored 13 publications receiving 1555 citations.
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Journal ArticleDOI
Large‐scale mapping of human protein–protein interactions by mass spectrometry
Rob M. Ewing,Peter Chu,Fred Elisma,Hongyan Li,Paul J. Taylor,Shane Climie,Linda McBroom-Cerajewski,Mark D. Robinson,Liam O'Connor,Michael Li,Rod Taylor,Moyez Dharsee,Yuen Ho,Adrian Heilbut,Lynda Moore,Shudong Zhang,Olga Ornatsky,Yury V. Bukhman,Martin Ethier,Yinglun Sheng,Julian Vasilescu,Mohamed Abu-Farha,Jean-Philippe Lambert,Henry S. Duewel,Ian I. Stewart,Bonnie Kuehl,Kelly Hogue,Karen Colwill,Katharine Gladwish,Brenda Muskat,Robert Kinach,Sally Lin Adams,Michael Moran,Gregg B. Morin,Thodoros Topaloglou,Daniel Figeys +35 more
TL;DR: In‐depth mining of the data set shows that it represents a valuable source of novel protein–protein interactions with relevance to human diseases, and via the preliminary analysis, many novel protein interactions and pathway associations are reported.
Journal ArticleDOI
Human Proteinpedia enables sharing of human protein data.
Suresh Mathivanan,Suresh Mathivanan,Mukhtar Ahmed,Natalie G. Ahn,Hainard Alexandre,Ramars Amanchy,Philip C. Andrews,Joel S. Bader,Brian M. Balgley,Marcus Bantscheff,Keiryn L. Bennett,Erik Björling,Blagoy Blagoev,Ron Bose,Samir K. Brahmachari,Alma S Burlingame,Xosé R. Bustelo,Gerard Cagney,Greg T. Cantin,Helene L. Cardasis,Julio E. Celis,Raghothama Chaerkady,Feixia Chu,Philip A. Cole,Catherine E. Costello,Robert J. Cotter,David K. Crockett,James P. DeLany,Angelo M. De Marzo,Leroi V. DeSouza,Eric W. Deutsch,E. Dransfield,Gerard Drewes,Arnaud Droit,Michael J. Dunn,Kojo S.J. Elenitoba-Johnson,Rob M. Ewing,Jennifer E. Van Eyk,Vitor M. Faça,Jayson A. Falkner,Xiangming Fang,Catherine Fenselau,Daniel Figeys,Pierre Gagné,Cecilia Gelfi,Kris Gevaert,Jeffrey M. Gimble,Florian Gnad,Renu Goel,Pavel Gromov,Samir M. Hanash,William S. Hancock,H. C. Harsha,Gerald W. Hart,Faith A. Hays,Fuchu He,Prashantha Hebbar,Kenny Helsens,Heiko Hermeking,Winston Hide,Karin Hjernø,Denis F. Hochstrasser,Oliver Hofmann,David M Horn,Ralph H. Hruban,Nieves Ibarrola,Peter James,Ole N. Jensen,Pia Hønnerup Jensen,Peter Jung,Kumaran Kandasamy,Kumaran Kandasamy,Indu Kheterpal,Reiko F. Kikuno,Ulrike Korf,Roman Körner,Bernhard Kuster,Min-Seok Kwon,Hyoung Joo Lee,Young Jin Lee,Michael Lefevre,Minna Lehvaslaiho,Pierre Lescuyer,Fredrik Levander,Megan S. Lim,Christian Löbke,Joseph A. Loo,Matthias Mann,Matthias Mann,Lennart Martens,Juan Martínez-Heredia,Mark E. McComb,James P. McRedmond,Alexander Mehrle,Rajasree Menon,Christine A. Miller,Harald Mischak,Subburaman Mohan,Riaz Mohmood,Henrik Molina,Michael Moran,James D. Morgan,Robert Moritz,Martine Morzel,David C. Muddiman,Anuradha Nalli,J. Daniel Navarro,Thomas A. Neubert,Osamu Ohara,Rafael Oliva,Gilbert S. Omenn,Masaaki Oyama,Young Ki Paik,Kyla Pennington,Rainer Pepperkok,Balamurugan Periaswamy,Balamurugan Periaswamy,Emanuel F. Petricoin,Guy G. Poirier,T. S. Keshava Prasad,Samuel O. Purvine,B. Abdul Rahiman,Prasanna Ramachandran,Y. L. Ramachandra,Robert H. Rice,Jens Rick,Ragna Rönnholm,Johanna Salonen,Jean-Charles Sanchez,Thierry Sayd,Beerelli Seshi,Kripa Shankari,Shi Jun Sheng,Vivekananda Shetty,K. Shivakumar,Richard J. Simpson,Ravi Sirdeshmukh,K. W. Michael Siu,Jeffrey C. Smith,Richard D. Smith,David J. States,Sumio Sugano,Matthew J. Sullivan,Giulio Superti-Furga,Maarit Takatalo,Visith Thongboonkerd,Jonathan C. Trinidad,Mathias Uhlén,Joël Vandekerckhove,Julian Vasilescu,Timothy D. Veenstra,Jose-Manuel Vidal-Taboada,Mauno Vihinen,Robin Wait,Xiaoyue Wang,Stefan Wiemann,Billy Wu,Tao Xu,John R. Yates,Jun Zhong,Ming Zhou,Yunping Zhu,Petra Zürbig,Akhilesh Pandey +163 more
TL;DR: MMCD is a practical tool for expediting the time-consuming steps of identifying and researching small molecules and is compatible with both NMR and MS data and facilitates high-throughput metabolomics investigations.
Journal ArticleDOI
Proteomic Analysis of Ubiquitinated Proteins from Human MCF-7 Breast Cancer Cells by Immunoaffinity Purification and Mass Spectrometry
TL;DR: A novel method for identifying ubiquitinated proteins from a complex biological sample, such as a whole cell lysate, using a combination of immunoaffinity purification and liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis is described.
Journal ArticleDOI
Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry
TL;DR: It is demonstrated that ubiquitination sites can be identified by signature peptides containing a GG‐tag and an LRGG‐tag on internal lysine residues as well as a GG-tag found on the C‐terminus of ubiquitinated peptides.
Book ChapterDOI
Biomarker Assay Translation from Discovery to Clinical Studies in Cancer Drug Development: Quantification of Emerging Protein Biomarkers
TL;DR: Many of the challenges faced during biomarker discovery as well as during technology and process translation are discussed in this chapter, including preanalytical planning, assay development, and preclinical and clinical validation.