D
Daniel H. Haft
Researcher at National Institutes of Health
Publications - 104
Citations - 52879
Daniel H. Haft is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 64, co-authored 97 publications receiving 45318 citations. Previous affiliations of Daniel H. Haft include TigerLogic & J. Craig Venter Institute.
Papers
More filters
Journal ArticleDOI
HMM-based databases in InterPro
Alex Bateman,Daniel H. Haft +1 more
TL;DR: This paper reviews the Pfam, TIGRFAMs and SMART databases that use the profile-HMMs provided by the HMMER package to find hidden Markov models used for protein evolution and function detection.
Journal ArticleDOI
Permuting the PGF Signature Motif Blocks both Archaeosortase-Dependent C-Terminal Cleavage and Prenyl Lipid Attachment for the Haloferax volcanii S-Layer Glycoprotein
Mohd Farid Abdul Halim,Kelly R. Karch,Yitian Zhou,Daniel H. Haft,Benjamin A. Garcia,Mechthild Pohlschroder +5 more
TL;DR: The first in vivo studies of a novel protein-anchoring pathway involving lipid modification of a peptidase-processed C terminus are reported, suggesting that ArtA is either directly or indirectly involved in a novel proteolysis-coupled, covalent lipid-mediated anchoring mechanism by prokaryotes.
Journal ArticleDOI
CharProtDB: a database of experimentally characterized protein annotations
Ramana Madupu,R. Alexander Richter,Robert J. Dodson,Lauren M. Brinkac,Derek M. Harkins,A. Scott Durkin,Susmita Shrivastava,Granger G. Sutton,Daniel H. Haft +8 more
TL;DR: The CharProtDB has been expanded by import of selected records from publicly available protein collections whose biocuration indicated direct rather than homology-based assignment of function.
Journal ArticleDOI
Simultaneous non-contiguous deletions using large synthetic DNA and site-specific recombinases
Radha Krishnakumar,Carissa Grose,Daniel H. Haft,Jayshree Zaveri,Nina Alperovich,Daniel G. Gibson,Chuck Merryman,John I. Glass +7 more
TL;DR: This method will greatly speed up the creation of reduced, modularized and optimized genomes through the integration of deletion analyses data, transcriptomics, synthetic biology and site-specific recombination.
Journal ArticleDOI
Both widespread PEP-CTERM proteins and exopolysaccharides are required for floc formation of Zoogloea resiniphila and other activated sludge bacteria.
Na Gao,Ming Xia,Jingcheng Dai,Dianzhen Yu,Weixing An,Shuyang Li,Shuangyuan Liu,Penghui He,Liping Zhang,Zhenbin Wu,Xuezhi Bi,Shouwen Chen,Daniel H. Haft,Dongru Qiu +13 more
TL;DR: This study demonstrates an additional requirement for a PEP-CTERM protein in Zoogloea resiniphila, a dominant AS bacterium harboring a large exopolysaccharide biosynthesis gene cluster.