Daniel Márquez-Arce

TL;DR: Analysis of viral characteristics of the envelopes of viruses from a phylogenetic cluster of LTNP-EC patients suggested that inefficient HIV-1 Env functions and signaling defects may contribute to the low viral replication capacity and transmissibility of the cluster viruses, suggesting a direct role in the LT NP-EC phenotype of these individuals.

TL;DR: In this paper, the authors summarize the knowledge of the interplay between autophagy and the early events of HIV-1 infection, and how auto-ophagy modulation could impair or benefit HIV infection and persistence.

TL;DR: The data suggest that Env clones from VNP individuals are fully functional and that the paradoxical CD4+ T cell count stability coexisting with high levels of viral replication is unrelated to Env function.

TL;DR: In this paper, a review of recent advances in the understanding of the mechanisms underlying ZIKV immune modulation and evasion that strongly condition viral pathogenesis is presented, which would certainly contribute to the development of anti-ZIKV strategies, drugs, and vaccines.

TL;DR: The results suggest that HDAC6 acts as an anti-HIV-1 restriction factor, limiting viral production and infection by targeting Pr55Gag and Vif and the P72xxP75 motif appears to be responsible, directly or indirectly, for the interaction of Nef withHDAC6.