R
Ricardo Madrid
Researcher at Spanish National Research Council
Publications - 27
Citations - 1061
Ricardo Madrid is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Signal transducing adaptor protein & Formins. The author has an hindex of 15, co-authored 23 publications receiving 972 citations. Previous affiliations of Ricardo Madrid include Hospital General Universitario Gregorio Marañón & French Institute of Health and Medical Research.
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Journal ArticleDOI
Polarized trafficking and surface expression of the AQP4 water channel are coordinated by serial and regulated interactions with different clathrin-adaptor complexes.
Ricardo Madrid,Sophie Le Maout,Marie-Bénédicte Barrault,Katy Janvier,Serge Benichou,Jean Mérot +5 more
TL;DR: It is shown that two independent C‐terminal signals determine AQP4 basolateral membrane targeting in epithelial MDCK cells, and stress‐induced kinase casein kinase (CK)II phosphorylates the Ser276 immediately preceding the tyrosine motif, increasing AQp4–μ3A interaction and enhancing AQP 4–lysosomal targeting and degradation.
Journal ArticleDOI
Nef-induced Alteration of the Early/Recycling Endosomal Compartment Correlates with Enhancement of HIV-1 Infectivity
Ricardo Madrid,Katy Janvier,Douglas Hitchin,John R. Day,Scott H. Coleman,Colleen M. Noviello,Jérôme Bouchet,Alexandre Benmerah,John C. Guatelli,John C. Guatelli,Serge Benichou +10 more
TL;DR: It is shown that Nef specifically disturbs the morphology of the early/recycling compartment, inducing a redistribution of early endosomal markers and a shortening of the tubular recycling endosome structures.
Journal ArticleDOI
Activation of the Rac-binding Partner FHOD1 Induces Actin Stress Fibers via a ROCK-dependent Mechanism *
Judith E. Gasteier,Ricardo Madrid,Ellen Krautkrämer,Sebastian Schröder,Walter Muranyi,Serge Benichou,Oliver T. Fackler +6 more
TL;DR: Results indicate that FHOD1 acts as an effector of Rac in actin rearrangements and transcriptional regulation and may provide a link for the Rac-dependent activation of the Rho cascade.
Journal ArticleDOI
The formin INF2 regulates basolateral-to-apical transcytosis and lumen formation in association with Cdc42 and MAL2.
Ricardo Madrid,Juan F. Aranda,Alejo E. Rodriguez-Fraticelli,Leandro N. Ventimiglia,Laura Andrés-Delgado,Mona Shehata,Susan Fanayan,Hamideh Shahheydari,Sergio Gómez,Alberto Jiménez,Fernando Martín-Belmonte,Jennifer A. Byrne,Miguel A. Alonso +12 more
TL;DR: The results reveal a functional mechanism whereby Cdc42, INF2, and MAL2 are sequentially ordered in a pathway dedicated to the regulation of transcytosis and lumen formation.
Journal ArticleDOI
The phospholipid scramblases 1 and 4 are cellular receptors for the secretory leukocyte protease inhibitor and interact with CD4 at the plasma membrane.
Bénédicte Py,Bénédicte Py,Stéphane Basmaciogullari,Stéphane Basmaciogullari,Jérôme Bouchet,Jérôme Bouchet,Marion Zarka,Marion Zarka,Ivan C. Moura,Ivan C. Moura,Marc Benhamou,Marc Benhamou,Renato C. Monteiro,Renato C. Monteiro,Hakim Hocini,Ricardo Madrid,Ricardo Madrid,Serge Benichou,Serge Benichou +18 more
TL;DR: It is confirmed that recombinant SLPI is able to inhibit HIV-1 infection of primary T lymphocytes, and it is shown that SLPI can also inhibit the transfer of HIV- 1 virions from primary monocyte-derived dendritic cells to autologous T lymphocyte.