D
Danielle Basore
Researcher at Rensselaer Polytechnic Institute
Publications - 4
Citations - 69
Danielle Basore is an academic researcher from Rensselaer Polytechnic Institute. The author has contributed to research in topics: Cutinase & Virus. The author has an hindex of 2, co-authored 3 publications receiving 55 citations. Previous affiliations of Danielle Basore include Mercy College.
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Journal ArticleDOI
Toward rational thermostabilization of Aspergillus oryzae cutinase: Insights into catalytic and structural stability.
Abhijit N. Shirke,Danielle Basore,Glenn L. Butterfoss,Richard Bonneau,Christopher Bystroff,Richard A. Gross +5 more
TL;DR: Three notable findings are presented as steps toward designing more thermophilic cutinase: surface salt bridge optimization produced enthalpic stabilization, mutations to proline reduced the entropy loss upon folding, and the lack of a correlative increase in the temperature optimum of catalytic activity with thermodynamic stability suggests that the active site is locally denatured at a temperature below the Tm of the global structure.
Journal ArticleDOI
Influence of surface charge, binding site residues and glycosylation on Thielavia terrestris cutinase biochemical characteristics
Abhijit N. Shirke,Danielle Basore,Samantha Holton,An Su,Evan H. Baugh,Glenn L. Butterfoss,George I. Makhatadze,Christopher Bystroff,Richard A. Gross +8 more
TL;DR: The stability of TtC in acidic pH was rationalized by evaluating the contribution of charge interactions to the Gibbs free energy of unfolding at varying pHs and the activity of TTC was found to be limited by substrate binding affinity, which is a function of the surface charge.
Journal ArticleDOI
HPV VLPs as Scaffolds for Vaccine Design
Thomas B. Jordan,Carolyn M. Barcellona,Danielle Basore,Charlie Clark,Zeyuan Guo,Sharon Isern,Kripa Nand,Gabi Rabasa,Terrence Shoemaker,Giffin Werner,Kai Xia,Xinmeng Yuan,Robert J. Linhardt,Scott F. Michael,Christopher Bystroff +14 more
Posted ContentDOI
Engineering a Universal Dengue Virus Vaccine using a Virus-Like Particle Scaffold
Danielle Basore,Carolyn M. Barcellona,Thomas B. Jordan,Donna E. Crone,Sharon Isern,Scott F. Michael,Christopher Bystroff +6 more
TL;DR: The authors have withdrawn their manuscript as it was submitted and made public without the full consent of all the authors and is not wish to be cited as reference for the project.