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Dario Perdicchia
Researcher at University of Milan
Publications - 52
Citations - 1260
Dario Perdicchia is an academic researcher from University of Milan. The author has contributed to research in topics: Carbene & Enantioselective synthesis. The author has an hindex of 16, co-authored 50 publications receiving 1074 citations. Previous affiliations of Dario Perdicchia include National Research Foundation of South Africa & Sapienza University of Rome.
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The 1,2,3-triazole ring as a bioisostere in medicinal chemistry
Elisa Bonandi,Michael S. Christodoulou,Gaia Fumagalli,Dario Perdicchia,Giulio Rastelli,Daniele Passarella +5 more
TL;DR: An overview of the 1,2,3-triazole ring as a bioisostere for the design of drug analogs, highlighting relevant recent examples.
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A convenient procedure for the synthesis of tetrathia-[7]-helicene and the selective α-functionalisation of terminal thiophene ring
Stefano Maiorana,Antonio Papagni,Emanuela Licandro,Rita Annunziata,Piero Paravidino,Dario Perdicchia,Clelia Giannini,Marco Bencini,Koen Clays,André Persoons +9 more
TL;DR: In this article, the α-anion of tetrathia-7]-helicene (TH[7] was generated on the terminal thiophene ring and the synthesis of the 2-formyl-tetrathyia-[7]- helicene was performed in 46% overall yield, which is more than four times the yield previously reported in the literature.
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N-Acylhydrazines: Future Perspectives Offered by New Syntheses and Chemistry
TL;DR: A review of the most recent and useful synthetic methodologies for providing access to di- and trisubstituted hydrazides is given in this article, with a focus on new chemistry and new organometallic derivatives of the title compounds, which are also useful as new biologically relevant molecules.
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Enzymatic Kinetic Resolution of 2-Piperidineethanol for the Enantioselective Targeted and Diversity Oriented Synthesis.
Dario Perdicchia,Michael S. Christodoulou,Gaia Fumagalli,Francesco Calogero,Cristina Marucci,Daniele Passarella +5 more
TL;DR: Both synthetic and enzymatic methods for the resolution of the racemic 1 are presented, as well as an overview of synthesized natural products starting from the enantiopure 1.
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Asymmetric aza-Michael reactions catalyzed by cinchona alkaloids.
TL;DR: The organocatalysed asymmetric aza-Michael addition of hydrazones to cyclic enones has been achieved in good yield and stereoselection using cheap and commercially available cinchona alkaloids as catalysts, leading to optically active products with up to 77% ee.