D
Darwin Yang
Researcher at University of California, Berkeley
Publications - 16
Citations - 683
Darwin Yang is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: Protein Corona & Nanosensor. The author has an hindex of 9, co-authored 16 publications receiving 374 citations.
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Journal ArticleDOI
Single-molecule detection of protein efflux from microorganisms using fluorescent single-walled carbon nanotube sensor arrays.
Markita P. Landry,Hiroki Ando,Allen Chen,Allen Chen,Jicong Cao,Vishal I. Kottadiel,Linda Chio,Darwin Yang,Juyao Dong,Timothy K. Lu,Michael S. Strano +10 more
TL;DR: In this article, the authors demonstrate label-free detection of individual proteins from Escherichia coli (bacteria) and Pichia pastoris (yeast) in a microfluidic chamber, measuring protein efflux from single organisms in real time.
Journal ArticleDOI
Imaging striatal dopamine release using a nongenetically encoded near infrared fluorescent catecholamine nanosensor.
Abraham G. Beyene,Kristen Delevich,Kristen Delevich,Jackson Travis Del Bonis-O'Donnell,David J. Piekarski,Wan Chen Lin,A. Wren Thomas,Sarah J. Yang,Polina Kosillo,Darwin Yang,George S. Prounis,Linda Wilbrecht,Linda Wilbrecht,Markita P. Landry +13 more
TL;DR: NIRCats can be used to measure electrically and optogenetically evoked dopamine release in brain tissue, revealing hotspots with a median size of 2 µm and it is demonstrated that nIRCats are compatible with dopamine pharmacology and show D2 autoreceptor modulation of evokes dopamine release.
Journal ArticleDOI
Rapid SARS-CoV-2 Spike Protein Detection by Carbon Nanotube-Based Near-Infrared Nanosensors.
Rebecca L. Pinals,Francis Ledesma,Darwin Yang,Nicole Navarro,Sanghwa Jeong,John E. Pak,Lili Kuo,Yung Chun Chuang,Yu Wei Cheng,Hung Yu Sun,Markita P. Landry +10 more
TL;DR: In this article, a single-walled carbon nanotube (SWCNT)-based optical sensing approach was proposed to detect SARS-CoV-2 virus-like particles.
Journal ArticleDOI
Quantitative Protein Corona Composition and Dynamics on Carbon Nanotubes in Biological Environments.
Rebecca L. Pinals,Darwin Yang,Daniel J. Rosenberg,Daniel J. Rosenberg,Tanya Chaudhary,Andrew R. Crothers,Anthony T. Iavarone,Michal Hammel,Markita P. Landry +8 more
TL;DR: This work measures protein corona formation on DNA-functionalized single-walled carbon nanotubes (ssDNA-SWCNTs), a nanoparticle ideal for sensing and delivery, in blood plasma and cerebrospinal fluid and characterize corona composition by mass spectrometry, revealing high-abundance corona proteins involved in lipid binding, complement activation, and coagulation.
Journal ArticleDOI
High-throughput evolution of near-infrared serotonin nanosensors
Sanghwa Jeong,Darwin Yang,Abraham G. Beyene,Jackson Travis Del Bonis-O'Donnell,Anneliese M.M. Gest,Nicole Navarro,Xiaoqi Sun,Markita P. Landry +7 more
TL;DR: This work introduces a generic platform to evolve synthetic molecular recognition on the surface of near-infrared fluorescent single-wall carbon nanotube (SWCNT) signal transducers and demonstrates evolution of molecular recognition toward neuromodulator serotonin generated from large libraries of ssDNA sequences conjugated to SWCNTs.