J W ten Cate

TL;DR: About 60% of patients with a first episode of proximal deep-vein thrombosis develop post-thrombotic syndrome within 2 years, and a sized-to-fit compression stocking reduced this rate by about 50%.

TL;DR: The results show that in humans endotoxin induces an early, rapidly counteracted fibrinolytic response, and a more long-lasting activation of thrombin by a mechanism other than contact system activation, and suggest that endotoxin-induced leukopenia and endothelial cell activation are mediated by TNF.

TL;DR: It is concluded that a single injection of tumor necrosis factor elicits a rapid and sustained activation of the common pathway of coagulation, probably induced through the extrinsic route and could play an important part in the earlyactivation of the hemostatic mechanism in septicemia.

TL;DR: There is a statistically significant and clinically important association between idiopathic venous thrombosis and the subsequent development of clinically overt cancer, especially among patients in whom venousThromboembolism recurs during follow-up.

TL;DR: It is concluded that fixed-dose subcutaneous LMWH is at least as effective and safe as intravenous adjusted-dose heparin in the initial treatment of symptomatic proximal-vein thrombosis and since there is no need for laboratory monitoring with the LMWH regimen, patients with venous thromBosis can be treated at home.