Showing papers by "Dat Q. Tran published in 1996"

TL;DR: Observations suggest that the PAHs dibenz[a,h]-anthracene, 6-hydroxy-chrysene, 2,3-benzofluorene, and benzo(a)pyrene may antagonize activity in yeast by binding to an anti-estrogen binding site on the hER or by mechanisms independent of the h ER.

TL;DR: The results suggest that the ability of the triazines to inhibit estrogen receptor-mediated responses in yeast occur through their interaction with hER and is dependent on the concentration of estradiol.

TL;DR: Results indicate that some synthetic chemicals directly inhibit the activity of hPR in yeast, suggesting a potential mechanism for the reported potent estrogenic activities of these chemicals.