David C. Dale

TL;DR: In vivo chemotactic ability of IFC neutrophils is slightly impaired, whereas that of FL cells is severely impaired; one-day storage of either cell concentrate causes further cell damage.

TL;DR: In eight patients with Wegener's granulomatosis effective cyclophosphamide therapy significantly reduced blood neutrophil, monocyte, and lymphocyte counts; lymphocytes counts were most severely reduced.

TL;DR: Implantation of transduced cells within this type of vascular graft may provide a useful approach for long-term local and systemic gene therapy.

TL;DR: It is demonstrated that G-CSF administered in vivo modulates PMNL-mediated fungicidal activity against the pseudohyphal form of C. albicans, thereby suggesting potential utility of G- CSF as a biologic response-modifying therapy in some opportunistic fungal infections.

TL;DR: Using data on the fraction of post‐mitotic neutrophil precursors (CD15+ cells) displaying positive markers for apoptosis in 12 normal humans, and a simple mathematical model, the apoptotic rate is estimated to be about 0.28/day in this compartment, implying that the influx of myelocytes into the post-mitotic compartment exceeds twice the granulocyte turnover rate (GTR).