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David Cabrera-García

Researcher at Columbia University

Publications -  15
Citations -  188

David Cabrera-García is an academic researcher from Columbia University. The author has contributed to research in topics: Palytoxin & Fibrinolysis. The author has an hindex of 6, co-authored 14 publications receiving 93 citations. Previous affiliations of David Cabrera-García include University of Oviedo & Netherlands Institute for Neuroscience.

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How many SARS-CoV-2 “viroporins” are really ion channels?

TL;DR: It is suggested below that a number of additional criteria need to be met in order for SARS-CoV-2 accessory proteins to be accepted as having ion channel activity, and that further work will be necessary.
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From the Cover: Selective Enhancement of Domoic Acid Toxicity in Primary Cultures of Cerebellar Granule Cells by Lowering Extracellular Na+ Concentration.

TL;DR: Evidence for an enhancement of excitotoxicity following exposure of cultured cerebellar granule cells to DOM in the presence of lower than physiological Na+ concentrations is presented and data suggest a crucial role for extracellular Na+ concentration in determining excittotoxicity by DOM is suggested.
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High levels of plasminogen activator inhibitor-1, tissue plasminogen activator and fibrinogen in patients with severe COVID-19

TL;DR: In this article, the authors measured plasma levels of fibrinogen, plasminogen, tissue PLASminogen activator (t-PA) and plasmogen activation inhibitor 1 (PAI-1) in blood from 37 patients with severe coronavirus disease-19 (COVID-19) and 23 controls.
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Early prediction of developing spontaneous activity in cultured neuronal networks.

TL;DR: In this paper, the authors used machine learning techniques to characterize and predict the developing spontaneous activity in mouse cortical neurons on microelectrode arrays (MEAs) during the first three weeks in vitro.
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Comparative Toxicological Study of the Novel Protein Phosphatase Inhibitor 19-Epi-Okadaic Acid in Primary Cultures of Rat Cerebellar Cells

TL;DR: 19-epi-OKA induced apoptotic condensation and fragmentation of chromatin, activation of caspases, and activation of ERK1/2 MAP kinases, features previously reported for OKA and dinophysistoxin-2.