David Gibson

TL;DR: Molecular pathways that appear to contribute to the immune imbalance and the cytokine dysregulation, which is associated with “inflammageing” or parainflammation are highlighted and suggested to delay age-related diseases and aging itself by suppressing pro-inflammatory molecular mechanisms or improving the timely resolution of inflammation.

TL;DR: Inhibition of TNF-alpha significantly improves vascular recovery within ischemic tissue and reduces pathological neovascularization in OIR, and provides a useful tool for mapping and quantifying tissue hypoxia in experimental isChemic retinopathy.

TL;DR: This study suggests that GOR-related aspiration plays a role in chronic cough in children with known GOR and Detecting pepsin in BAL fluid may therefore become an important adjunct in patient selection for antireflux surgery.

TL;DR: This review provides detail on the involvement of the NLRP3 inflammasome in OA pathology and how its members could act as potential biomarkers to assist clinical decisions.

TL;DR: Assessment of genome-wide DNA methylation changes specifically associated with ulcerative colitis, Crohn's disease and IBD activity provides new insights into differential epigenetic regulation of genes and molecular pathways, which may contribute to the pathogenesis and activity of IBD.