David L. Earnest

TL;DR: A randomized trial to determine whether dietary supplementation with wheat-bran fiber reduces the rate of recurrence of colorectal adenomas and found that it does not.

TL;DR: The results of these studies demonstrated that none of the control rats fed the various diets injected with AOM-vehicle developed tumors, and demonstrate for the first time that supplemental dietary ursodeoxycholic acid is a chemopreventive agent in the AOM model of experimental colonic carcinogenesis.

TL;DR: Results indicate that different bile acids exhibit distinct biological activities and suggest that the cytotoxicity reported for DCA may be due to its capacity to induce apoptosis via a protein kinase C-dependent signaling pathway.

TL;DR: It is suggested that a significant subset of typical heartburn sufferers have a lower threshold for esophageal sensation and pain, which may influence options for pharmacological intervention in such subjects.

TL;DR: All drugs were found to be superior to placebo, but alosetron and ramosetrons appeared to be the most effective.