D
David L. Hoover
Researcher at University of Maryland, Baltimore
Publications - 12
Citations - 649
David L. Hoover is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Brucella melitensis & Immunity. The author has an hindex of 10, co-authored 12 publications receiving 623 citations. Previous affiliations of David L. Hoover include Johns Hopkins University & University of Maryland, College Park.
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Journal ArticleDOI
Immunity of cholera in man: Relative role of antibacterial versus antitoxic immunity
Myron M. Levine,David R. Nalin,John P. Craig,David L. Hoover,Eric Bergquist,Daniel Waterman,H. Preston Holley,Richard B. Hornick,Nathaniel P. Pierce,Joseph P. Libonati +9 more
TL;DR: Failure to culture vibrios from intestinal fluid or stool of re-challenge volunteers suggests that the predominant immune mechanism is antibacterial rather than antitoxic.
Journal ArticleDOI
Immunity to Enterotoxigenic Escherichia coli
Myron M. Levine,David R. Nalin,David L. Hoover,Erick J. Bergquist,Richard B. Hornick,C R Young +5 more
TL;DR: These studies demonstrate that prior disease due to enterotoxigenic E. coli confers homologous immunity against subsequent challenge, and the operative mechanism apparently is not bactericidal and is not mediated by serum anti-O antibodies.
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Cholera, non-vibrio cholera, and stomach acid.
D. R. Nalin,D. R. Nalin,Myron M. Levine,Myron M. Levine,Eric Bergquist,Eric Bergquist,Joe Libonati,Joe Libonati,RichardJ. Levine,RichardJ. Levine,David L. Hoover,David L. Hoover,J.C. Mclaughlin,J.C. Mclaughlin,Jainul Alam,Jainul Alam,Richard B. Hornick,Richard B. Hornick +17 more
TL;DR: Investigation of fasting and postprandial stomach acid production in convalescent Bangalee cholera patients indicates that Idiopathic tropical hypochlorhydria may be a major factor accounting for the high incidence of diarrhoea due to acid-sensitive pathogens in developing countries.
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Pathologic changes associated with brucellosis experimentally induced by aerosol exposure in rhesus macaques (Macaca mulatta).
TL;DR: Pathologic findings in rhesus macaques after aerosol exposure to B melitensis are similar to those observed in humans with brucellosis, which may aid in the development of a vaccine against bru cellosis that can be used in humans.
Journal ArticleDOI
Bacteriologic and histologic features in mice after intranasal inoculation of Brucella melitensis.
Mark G. Mense,Van De Verg Ll,Apurba K. Bhattacharjee,Garrett Jl,Hart Ja,Lindler Le,T L Hadfield,David L. Hoover +7 more
TL;DR: Changes in the spleen and liver increased with increases in dose and with increased time following intranasal inoculation with B melitensis 16M, and surprisingly, histologic changes were not observed in the lungs of inoculated mice.