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David W. Dietz
Researcher at University Hospitals of Cleveland
Publications - 97
Citations - 4904
David W. Dietz is an academic researcher from University Hospitals of Cleveland. The author has contributed to research in topics: Colorectal cancer & Neoadjuvant therapy. The author has an hindex of 37, co-authored 93 publications receiving 4301 citations. Previous affiliations of David W. Dietz include Temple University & Washington University in St. Louis.
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Journal ArticleDOI
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial
Julio Garcia-Aguilar,Oliver S. Chow,David D. Smith,Jorge E. Marcet,Peter A. Cataldo,Madhulika G. Varma,Anjali S. Kumar,Samuel Oommen,Theodore Coutsoftides,Steven R. Hunt,Michael J. Stamos,Charles A. Ternent,Daniel O. Herzig,Alessandro Fichera,Blase N. Polite,David W. Dietz,Sujata Patil,Karin Avila +17 more
TL;DR: Delivery of mFOLFOX6 after chemoradiation and before total mesorectal excision has the potential to increase the proportion of patients eligible for less invasive treatment strategies; this strategy is being tested in phase 3 clinical trials.
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Predictive factors of pathologic complete response after neoadjuvant chemoradiation for rectal cancer.
Matthew F. Kalady,Luiz Felipe de Campos-Lobato,Luca Stocchi,Daniel P. Geisler,David W. Dietz,Ian C. Lavery,Victor W. Fazio +6 more
TL;DR: Despite traditional beliefs that certain patient and tumor factors influence pCR, an extended interval between completion of neoadjuvant therapy and surgery was the single most important determinant in achieving a pCR.
Journal ArticleDOI
Fibrin glue treatment of complex anal fistulas has low success rate.
Rasmy Loungnarath,David W. Dietz,Matthew G. Mutch,Elisa H. Birnbaum,Ira J. Kodner,James W. Fleshman +5 more
TL;DR: Fibrin glue treatment for complex anal fistulas has a low success rate and most recrudescences occurred within three months, however, given the low morbidity and relative simplicity of the procedure, fibr in glue should still be considered as a first-line treatment for patients with complex anal Fistulas.
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Pathologic Complete Response After Neoadjuvant Treatment for Rectal Cancer Decreases Distant Recurrence and Could Eradicate Local Recurrence
Luiz Felipe de Campos-Lobato,Luca Stocchi,Andre da Luz Moreira,Daniel P. Geisler,David W. Dietz,Ian C. Lavery,Victor W. Fazio,Matthew F. Kalady +7 more
TL;DR: Overall survival and distant recurrence were also significantly improved for patients achieving pCR, suggestingchievement of pCR after neoadjuvant chemoradiation is associated with greatly improved cancer outcomes in locally advanced rectal cancer.
Journal ArticleDOI
Fdg-pet/ct in the evaluation of anal carcinoma
Shane E. Cotter,Perry W. Grigsby,Barry A. Siegel,Farrokh Dehdashti,Robert S. Malyapa,Robert S. Malyapa,James W. Fleshman,Elisa H. Birnbaum,Xia Wang,Elliot E. Abbey,Benjamin R. Tan,Ira J. Kodner,Steven R. Hunt,Jennifer K. Lowney,Matthew G. Mutch,David W. Dietz,Robert J. Myerson +16 more
TL;DR: FDG-PET/CT detects substantially more abnormal inguinal lymph nodes than are identified by standard clinical staging with CT and physical examination, and detects the primary tumor more often than CT.