D
Debora Levy
Researcher at University of São Paulo
Publications - 70
Citations - 1029
Debora Levy is an academic researcher from University of São Paulo. The author has contributed to research in topics: Oxysterol & Medicine. The author has an hindex of 14, co-authored 62 publications receiving 616 citations.
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Journal ArticleDOI
Ferroptosis Mechanisms Involved in Neurodegenerative Diseases.
Cadiele Oliana Reichert,Fábio Alessandro de Freitas,Juliana Sampaio-Silva,Leonardo Rokita-Rosa,Priscila de Lima Barros,Debora Levy,Sérgio Paulo Bydlowski,Sérgio Paulo Bydlowski +7 more
TL;DR: The main mechanisms involved in the process of ferroptosis such as lipid peroxidation, glutathione peroxidase 4 enzyme activity, and iron metabolism are reviewed.
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Mastoparan induces apoptosis in B16F10-Nex2 melanoma cells via the intrinsic mitochondrial pathway and displays antitumor activity in vivo
Ricardo A. Azevedo,Carlos R. Figueiredo,Adilson Kleber Ferreira,Alisson L. Matsuo,Mariana H. Massaoka,Natalia Girola,Aline Vivian Vatti Auada,Camyla F. Farias,Kerly Fernanda Mesquita Pasqualoto,Cecilia Pessoa Rodrigues,José Alexandre Marzagão Barbuto,Debora Levy,Sérgio Paulo Bydlowski,Paulo L. de Sá-Junior,Luiz R. Travassos,Ivo Lebrun +15 more
TL;DR: The present results show that mastoparan induced caspase-dependent apoptosis in melanoma cells through the intrinsic mitochondrial pathway protecting the mice against tumor development.
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The Effect of Ursolic Acid on Leishmania (Leishmania) amazonensis Is Related to Programed Cell Death and Presents Therapeutic Potential in Experimental Cutaneous Leishmaniasis.
Eduardo S. Yamamoto,Bruno Luiz Soares Campos,Jéssica Adriana Jesus,Márcia Dalastra Laurenti,Susan Pereira Ribeiro,Susan Pereira Ribeiro,Esper G. Kallas,Mariana Rafael-Fernandes,Gabriela Santos-Gomes,Marcelo Silva,Deborah P. Sessa,João Henrique G. Lago,Debora Levy,Luiz Felipe Domingues Passero +13 more
TL;DR: It is shown, for the first time, that UA eliminate promastigote forms through a mechanism associated with programed cell death, and importantly, was effective in vivo.
Journal ArticleDOI
Hepcidin: Homeostasis and Diseases Related to Iron Metabolism.
Cadiele Oliana Reichert,Joel da Cunha,Debora Levy,Luciana Morganti Ferreira Maselli,Sérgio Paulo Bydlowski,Celso Spada +5 more
TL;DR: This review describes the main pathways of systemic and genetic regulation of hepcidin, as well as its influence on the disorders related to iron metabolism, including iron-refractory anaemia and haemochromatosis.
Journal ArticleDOI
Apoptotic effect of eugenol envolves G2/M phase abrogation accompanied by mitochondrial damage and clastogenic effect on cancer cell in vitro.
Paulo Luiz de Sá Júnior,Diana Aparecida Dias Câmara,André Santos Costa,Jorge Luis Maria Ruiz,Debora Levy,Ricardo A. Azevedo,Kerly Fernanda Mesquita Pasqualoto,Camila Fávero de Oliveira,Thatiana Correa de Melo,Nara Diniz Soares Pessoa,Pâmela Maria Moreira Fonseca,Alexandre Pereira,Rodrigo Pinheiro Araldi,Adilson Kleber Ferreira +13 more
TL;DR: New light is shed on the mechanisms of action of EUG suggesting a possible applicability of this phenylpropanoid as adjuvant in anti-cancer therapy.