D
Deborah E. Devor
Researcher at National Institutes of Health
Publications - 26
Citations - 1292
Deborah E. Devor is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Carcinogenesis & Hepatocyte. The author has an hindex of 17, co-authored 26 publications receiving 1270 citations.
Papers
More filters
Journal ArticleDOI
Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice.
James R. Gnarra,Jerrold M. Ward,Forbes D. Porter,Joseph Wagner,Deborah E. Devor,Alex Grinberg,Michael R. Emmert-Buck,Heiner Westphal,Richard D. Klausner,W. Marston Linehan +9 more
TL;DR: Results indicate that VHL expression is critical for normal extraembryonic vascular development and that somatic VHL inactivation is an early genetic event leading to the development of sporadic renal cell carcinoma.
Journal Article
Cadmium carcinogenesis in male Wistar [Crl:(WI)BR] rats: dose-response analysis of tumor induction in the prostate and testes and at the injection site
Michael P. Waalkes,Sabine Rehm,Charles W. Riggs,Robert M. Bare,Deborah E. Devor,Lionel A. Poirier,Martin L. Wenk,John R. Henneman,Michael Balaschak +8 more
TL;DR: It is indicated that CdCl2 can induce preneoplastic lesions of the prostate that appear to develop into tumors only at doses well below those causing marked degeneration of the testes and atrophy of the prostatic atrophy.
Journal Article
Comparison of two-stage epidermal carcinogenesis initiated by 7,12-dimethylbenz(a)anthracene or N-methyl-N'-nitro-N-nitrosoguanidine in newborn and adult SENCAR and BALB/c mice.
Henry Hennings,Deborah E. Devor,Martin L. Wenk,Thomas J. Slaga,Brigitte F. Former,Nancy H. Colburn,G. T. Bowden,Kjell Elgjo,Stuart H. Yuspa +8 more
TL;DR: The increased sensitivity of SENCAR's was apparent regardless of route of administration of initiator or the age or sex of the mice, which suggests that enhanced metabolic activation of hydrocarbon carcinogens by SENCAR mice is unlikely to account for their sensitivity.
Journal Article
Cadmium carcinogenesis in male Wistar [Crl:(WI)BR[ rats: dose-response analysis of effects of zinc on tumor induction in the prostate, in the testes, and at the injection site
Michael P. Waalkes,Sabine Rehm,Charles W. Riggs,Robert M. Bare,Deborah E. Devor,Lionel A. Poirier,Martin L. Wenk,John R. Henneman +7 more
TL;DR: The results indicate that zinc inhibition of cadmium carcinogenesis is a complex phenomenon, depending not only on dose and route but also on the target site in question.
Journal Article
Progression of prostatic intraepithelial neoplasia to invasive carcinoma in C3(1)/SV40 large T antigen transgenic mice: histopathological and molecular biological alterations
TL;DR: It is concluded that high-grade PIN is a precursor lesion of prostate carcinoma in this transgenic model of C3(1)/T(AG) transgenic mice, and may occur during the development of prostate cancer in humans.