S
Stuart H. Yuspa
Researcher at National Institutes of Health
Publications - Â 371
Citations - Â 28231
Stuart H. Yuspa is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Keratinocyte & Carcinogenesis. The author has an hindex of 86, co-authored 367 publications receiving 27437 citations. Previous affiliations of Stuart H. Yuspa include MSC Industrial Direct Company, Inc..
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Journal ArticleDOI
Calcium regulation of growth and differentiation of mouse epidermal cells in culture
Henry Hennings,Delores Michael,Christina Cheng,Peter M. Steinert,Karen A. Holbrook,Stuart H. Yuspa +5 more
TL;DR: Ulastructural examination of cells cultured under low Ca++ conditions reveals widened intercellular spaces, abundant microvilli and perinuclear organization of tonofilaments and cellular organelles.
Journal ArticleDOI
Targeted Disruption of Mouse EGF Receptor: Effect of Genetic Background on Mutant Phenotype
David W. Threadgill,Andrzej A. Dlugosz,Laura A. Hansen,Tamar Tennenbaum,Ulrike Lichti,Della Yee,Christian LaMantia,Tracy Mourton,Karl Herrup,Raymond C. Harris,John A. Barnard,Stuart H. Yuspa,Robert J. Coffey,Terry Magnuson +13 more
TL;DR: The multiple abnormalities associated with EGFR deficiency indicate that the receptor is involved in a wide range of cellular activities.
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Characterization of bullous pemphigoid antigen: A unique basement membrane protein of stratified squamous epithelia
TL;DR: It is demonstrated that BP antigen is synthesized by epidermal cells in culture, different patients with BP have antibodies against the same protein, and BP antigen can be identified on SDS-PAGE as a high molecular weight protein consisting of disulfide-linked chains of approximate molecular weight 220 kd.
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Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro.
TL;DR: In vitro results suggest that the Ca2+ environment is a fundamental regulator of expression of epidermal differentiation markers and provide an explanation for the existence of theCa2+ gradient in vivo.
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Identification of a major keratinocyte cell envelope protein, loricrin.
Thomas Mehrel,Daniel Hohl,Joseph A. Rothnagel,Mary A. Longley,Donnie S. Bundman,Christina Cheng,Ulrike Lichti,M. E. Bisher,Alasdair C. Steven,Peter M. Steinert,Stuart H. Yuspa,Dennis R. Roop +11 more
TL;DR: CDNA clones encoding a major differentiation product of mouse epidermal cells are isolated and characterized, which has an amino acid composition similar to that of purified cell envelopes and is named loricrin on the basis of its presumed function.