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Debra H. Brinkmann
Researcher at Mayo Clinic
Publications - 41
Citations - 1328
Debra H. Brinkmann is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 13, co-authored 35 publications receiving 1008 citations. Previous affiliations of Debra H. Brinkmann include University of Minnesota.
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Journal ArticleDOI
Is the blood-brain barrier really disrupted in all glioblastomas? A critical assessment of existing clinical data.
Jann N. Sarkaria,Leland S. Hu,Ian F. Parney,Deanna H. Pafundi,Debra H. Brinkmann,Nadia N. Laack,Caterina Giannini,Terence C. Burns,Sani H. Kizilbash,Janice K. Laramy,Kristin R. Swanson,Timothy J. Kaufmann,Paul D. Brown,Nathalie Y. R. Agar,Evanthia Galanis,Jan C. Buckner,William F. Elmquist +16 more
TL;DR: This review provides an overview of the clinical literature to support a central hypothesis: that all GBM patients have tumor regions with an intact BBB, and cure for GBM will only be possible if these regions of tumor are adequately treated.
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Biopsy validation of 18F-DOPA PET and biodistribution in gliomas for neurosurgical planning and radiotherapy target delineation: results of a prospective pilot study
Deanna H. Pafundi,Nadia N. Laack,Ryan S. Youland,Ian F. Parney,Val J. Lowe,Caterina Giannini,Brad Kemp,Michael P. Grams,Jonathan M. Morris,Jason M. Hoover,Leland S. Hu,Jann N. Sarkaria,Debra H. Brinkmann +12 more
TL;DR: F-DOPA PET SUV(max) may more accurately identify regions of higher-grade/higher-density disease in patients with astrocytomas and will have utility in guiding stereotactic biopsy selection.
Journal ArticleDOI
Incidence of radiation pneumonitis after thoracic irradiation: Dose-volume correlates.
TL;DR: Intrathoracic radiotherapy should be planned with caution when using radiotherapy techniques delivering doses of 10 to 15 Gy to large lung volumes, with a decrease in predictive value above those volumes.
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The role of LAT1 in 18 F-DOPA uptake in malignant gliomas
Ryan S. Youland,Gaspar J. Kitange,Timothy E. Peterson,Deanna H. Pafundi,Judi Ramiscal,Jenny L. Pokorny,Caterina Giannini,Nadia N. Laack,Ian F. Parney,Val J. Lowe,Debra H. Brinkmann,Jann N. Sarkaria +11 more
TL;DR: In this article, the relationship between LAT1 expression and 18F-DOPA uptake in human glioblastoma (GBM) cells was investigated using Western blotting and reverse transcription polymerase chain reaction (qRT-PCR).
Journal ArticleDOI
Stereotactic body radiation therapy in spinal metastases
Kamran Ahmed,Michael C. Stauder,Robert C. Miller,Heather J. Bauer,Peter S. Rose,Kenneth R. Olivier,Paul D. Brown,Debra H. Brinkmann,Nadia N. Laack +8 more
TL;DR: Results indicate SBRT to be an effective measure to achieve local control in spinal metastases and further research is needed to determine optimum dose and fractionation to further improve local control and prevent toxicity.