D
Dechun Geng
Researcher at Soochow University (Suzhou)
Publications - 139
Citations - 2448
Dechun Geng is an academic researcher from Soochow University (Suzhou). The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 20, co-authored 91 publications receiving 1261 citations.
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Journal ArticleDOI
A Comparison of the Proximal Femoral Nail Antirotation Device and Dynamic Hip Screw in the Treatment of Unstable Pertrochanteric Fracture
TL;DR: The PFNA allowed earlier mobilization and faster recovery than the DHS, and time to mobilization with a frame was significantly shorter in the PFNA, and post-operative complications were more common in the DHS group.
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Icariin protects against titanium particle-induced osteolysis and inflammatory response in a mouse calvarial model
Hongguo Shao,Ji Shen,Mingjun Wang,Jingfu Cui,Yijun Wang,Shijun Zhu,Wen Zhang,Huilin Yang,Yaozeng Xu,Dechun Geng +9 more
TL;DR: It is suggested that icariin represents a potential treatment for titanium particle-induced osteolysis and could be developed as a new therapeutic candidate for the prevention and treatment of aseptic loosening.
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Inhibitory effects of melatonin on titanium particle-induced inflammatory bone resorption and osteoclastogenesis via suppression of NF-κB signaling.
Zichuan Ping,Zhirong Wang,Jiawei Shi,Liangliang Wang,Xiaobin Guo,Wei Zhou,Xuanyang Hu,Xiexing Wu,Yu Liu,Wen Zhang,Huilin Yang,Yaozeng Xu,Ye Gu,Dechun Geng +13 more
TL;DR: It is found that the exogenous administration of melatonin significantly inhibited wear debris-induced bone resorption and the expression of inflammatory cytokines in vivo and melatonin inhibits receptor activator of nuclear factor kappa-B ligand induced osteoclast formation and osteoclastic bone Resorption in vitro.
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Biomimetic osteogenic peptide with mussel adhesion and osteoimmunomodulatory functions to ameliorate interfacial osseointegration under chronic inflammation.
Jiaxiang Bai,Huaiyu Wang,Hao Chen,Gaoran Ge,Miao Wang,Ang Gao,Liping Tong,Yaozeng Xu,Huiling Yang,Guoqing Pan,Paul K. Chu,Dechun Geng +11 more
TL;DR: It is indicated that biomimetic peptides with osteoimmunomodulatory bioactivity can be incorporated into Ti-based prostheses to facilitate bone regeneration in patients with chronic inflammatory diseases.
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Inhibition of titanium-particle-induced inflammatory osteolysis after local administration of dopamine and suppression of osteoclastogenesis via D2-like receptor signaling pathway.
Huilin Yang,Yaozeng Xu,Mo Zhu,Ye Gu,Wen Zhang,Hongguo Shao,Yijun Wang,Zichuan Ping,Xuanyang Hu,Liangliang Wang,Dechun Geng +10 more
TL;DR: Dopamine therapy could be developed into an effective and safe method for osteolysis-related disease caused by chronic inflammation and excessive osteoclast formation.