D
Delmiro Fernandez-Reyes
Researcher at University College London
Publications - 62
Citations - 2046
Delmiro Fernandez-Reyes is an academic researcher from University College London. The author has contributed to research in topics: Malaria & Plasmodium falciparum. The author has an hindex of 20, co-authored 54 publications receiving 1770 citations. Previous affiliations of Delmiro Fernandez-Reyes include National Institute for Medical Research & John Radcliffe Hospital.
Papers
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Journal ArticleDOI
Identification of diagnostic markers for tuberculosis by proteomic fingerprinting of serum
Dan Agranoff,Delmiro Fernandez-Reyes,Delmiro Fernandez-Reyes,Marios C. Papadopoulos,Sergio A. Rojas,Sergio A. Rojas,Mark Herbster,Alison Loosemore,Edward Tarelli,Jo Sheldon,Achim Schwenk,Richard Pollok,Charlotte F. J. Rayner,Sanjeev Krishna +13 more
TL;DR: The potential biomarkers for tuberculosis that are identified through proteomic fingerprinting and pattern recognition have a plausible biological connection with the disease and could be used to develop new diagnostic tests.
Journal Article
Identification of diagnostic markers for tuberculosis by proteomic fingerprinting of serum. Commentary
Melanie Y. White,Rebekah L. Gundry,Stuart J. Cordwell,Dan Agranoff,Delmiro Fernandez-Reyes,Marios C. Papadopoulos,Sergio A. Rojas,Mark Herbster,Alison Loosemore,Edward Tarelli,Jo Sheldon,Achim Schwenk,Richard Pollok,Charlotte F. J. Rayner,Sanjeev Krishna +14 more
TL;DR: In this paper, a supervised machine-learning approach based on the support vector machine (SVM) was used to obtain a classifier that distinguished between the groups in two independent test sets.
Journal ArticleDOI
A High Frequency African Coding Polymorphism in the N-Terminal Domain of ICAM-1 Predisposing to Cerebral Malaria in Kenya
Delmiro Fernandez-Reyes,Alister Craig,S Kyes,Norbert Peshu,Robert W. Snow,Anthony R. Berendt,Kevin Marsh,Chris I. Newbold +7 more
TL;DR: Genotypes at this locus from samples from a case-control study indicated an association of the polymorphism with the severity of clinical malaria such that individuals homozygous for the mutation have increased susceptibility to cerebral malaria with a relative risk of two.
Journal ArticleDOI
Cytoadherence, pathogenesis and the infected red cell surface in Plasmodium falciparum.
TL;DR: The data on the molecular basis of interactions on both the host and parasite surfaces are summarized, the evidence for the involvement of particular receptors in specific disease syndromes is reviewed and the relevance of these data to the development of new treatments for malaria is discussed.
Journal ArticleDOI
The merozoite surface protein 6 gene codes for a 36 kDa protein associated with the Plasmodium falciparum merozoite surface protein-1 complex.
Carlotta Trucco,Delmiro Fernandez-Reyes,Steven Howell,William Stafford,Terry J. Scott-Finnigan,Munira Grainger,Solabomi A. Ogun,William R. Taylor,Anthony A. Holder +8 more
TL;DR: A complex of non-covalently bound polypeptides is located on the surface of the merozoite form of the human malaria parasite Plasmodium falciparum and the gene identified codes for MSP-6(36) has been determined, the corresponding gene cloned, and the protein characterised.