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Deming Xiao
Researcher at Peking University
Publications - 5
Citations - 252
Deming Xiao is an academic researcher from Peking University. The author has contributed to research in topics: PLGA & Transactivation. The author has an hindex of 3, co-authored 5 publications receiving 208 citations.
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Journal ArticleDOI
Resveratrol inhibits interleukin 1β-mediated inducible nitric oxide synthase expression in articular chondrocytes by activating SIRT1 and thereby suppressing nuclear factor-κB activity
Ming Lei,Ji-guo Wang,Deming Xiao,Meng Fan,Da-ping Wang,Jian-yi Xiong,Yang Chen,Yue Ding,Shang-li Liu +8 more
TL;DR: SIRT1 protects against the inflammatory response induced by IL-1β in articular chondrocytes and merits consideration as a therapeutic agent in the treatment and prevention of osteoarthritis.
Journal ArticleDOI
Phytomolecule icaritin incorporated PLGA/TCP scaffold for steroid-associated osteonecrosis: Proof-of-concept for prevention of hip joint collapse in bipedal emus and mechanistic study in quadrupedal rabbits
Ling Qin,Ling Qin,Dong Yao,Lizhen Zheng,Wai Ching Liu,Zhong Liu,Ming Lei,Le Huang,Xinhui Xie,Xinluan Wang,Yang Chen,Xin-Sheng Yao,Jiang Peng,He Gong,James F. Griffith,Yanping Huang,Yongping Zheng,Jian Q. Feng,Ying Liu,Shihui Chen,Deming Xiao,Daping Wang,Jiangyi Xiong,Duanqing Pei,Peng Zhang,Xiaohua Pan,Xiaohong Wang,Kwong Man Lee,Chun Yiu Cheng +28 more
TL;DR: Both efficacy and mechanistic studies show the potential of a bioactive composite porous P/T scaffold incorporating icaritin to enhance bone defect repair after surgical CD and prevent femoral head collapse in a bipedal SAON emu model.
Journal ArticleDOI
PLGA/TCP composite scaffold incorporating bioactive phytomolecule icaritin for enhancement of bone defect repair in rabbits.
Shi Hui Chen,Ming Lei,Xinhui Xie,Xinhui Xie,Lizhen Zheng,Dong Yao,Xinluan Wang,Xinluan Wang,Wei Li,Zhihe Zhao,A. Kong,Deming Xiao,D.-P. Wang,X.-H. Pan,Y.-X. Wang,Ling Qin,Ling Qin +16 more
TL;DR: X-ray and high-resolution peripheral quantitative computed tomography results at weeks 2, 4 and 8 post-surgery showed more newly formed bone within bone defects implanted withPLGA/TCP/ICT scaffolds, especially PLGA/ TCP/MICT scaffold, which may form a good foundation for potential clinical validation of this innovative bioactive scaffold incorporated with the proper amount of osteopromotive phytomolecule ICT.