D
Denisse Ambler
Researcher at University of North Carolina at Chapel Hill
Publications - 4
Citations - 600
Denisse Ambler is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Schizophrenia & Psychopathology. The author has an hindex of 3, co-authored 4 publications receiving 575 citations.
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Double-blind comparison of first- and second-generation antipsychotics in early-onset schizophrenia and schizo-affective disorder: findings from the treatment of early-onset schizophrenia spectrum disorders (TEOSS) study
Linmarie Sikich,Jean A. Frazier,Jon McClellan,Robert L. Findling,Benedetto Vitiello,Louise Ritz,Denisse Ambler,Madeline Puglia,Ann E. Maloney,Emily S. Michael,Sandra De Jong,Karen Slifka,Nancy Noyes,Stefanie A. Hlastala,Leslie Pierson,Nora K. McNamara,Denise Delporto-Bedoya,Robert H. Anderson,Robert M. Hamer,Jeffrey A. Lieberman +19 more
TL;DR: The results question the nearly exclusive use of second-generation antipsychotics to treat early-onset schizophrenia and schizoaffective disorder and the safety findings related to weight gain and metabolic problems raise important public health concerns.
Journal ArticleDOI
Treatment of early-onset schizophrenia spectrum disorders (TEOSS): demographic and clinical characteristics.
Jean A. Frazier,Jon McClellan,Robert L. Findling,Benedetto Vitiello,Robert H. Anderson,Benjamin Zablotsky,Emily A. Williams,Nora K. McNamara,Joseph A. Jackson,Louise Ritz,Stefanie A. Hlastala,Leslie Pierson,Jennifer A. Varley,Madeline Puglia,Ann E. Maloney,Denisse Ambler,Tyehimba Hunt-Harrison,Robert M. Hamer,Nancy Noyes,Jeffrey A. Lieberman,Linmarie Sikich +20 more
TL;DR: A comparison to published reports of adults with SZ indicates that these youths may have more severe symptoms based on results of the Positive and Negative Symptom Scale, and the symptom profiles are consistent with, but more severe than, those reported in the adult literature.
Journal ArticleDOI
Treatment of Early-Onset Schizophrenia Spectrum Disorders (TEOSS): Rationale, Design, and Methods
Jon McClellan,Linmarie Sikich,Robert L. Findling,Jean A. Frazier,Benedetto Vitiello,Stefanie A. Hlastala,Emily A. Williams,Denisse Ambler,Tyehimba Hunt-Harrison,Ann E. Maloney,Louise Ritz,Robert H. Anderson,Robert M. Hamer,Jeffrey A. Lieberman +13 more
TL;DR: The Treatment of Early Onset Schizophrenia Spectrum Disorders Study will inform clinical practice regarding the use of antipsychotic medications for youths with early-onset schizophrenia spectrum disorders.