L
Leslie Pierson
Researcher at Seattle Children's
Publications - 3
Citations - 593
Leslie Pierson is an academic researcher from Seattle Children's. The author has contributed to research in topics: Schizoaffective disorder & Olanzapine. The author has an hindex of 3, co-authored 3 publications receiving 564 citations. Previous affiliations of Leslie Pierson include University of Washington.
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Journal ArticleDOI
Double-blind comparison of first- and second-generation antipsychotics in early-onset schizophrenia and schizo-affective disorder: findings from the treatment of early-onset schizophrenia spectrum disorders (TEOSS) study
Linmarie Sikich,Jean A. Frazier,Jon McClellan,Robert L. Findling,Benedetto Vitiello,Louise Ritz,Denisse Ambler,Madeline Puglia,Ann E. Maloney,Emily S. Michael,Sandra De Jong,Karen Slifka,Nancy Noyes,Stefanie A. Hlastala,Leslie Pierson,Nora K. McNamara,Denise Delporto-Bedoya,Robert H. Anderson,Robert M. Hamer,Jeffrey A. Lieberman +19 more
TL;DR: The results question the nearly exclusive use of second-generation antipsychotics to treat early-onset schizophrenia and schizoaffective disorder and the safety findings related to weight gain and metabolic problems raise important public health concerns.
Journal ArticleDOI
Treatment of early-onset schizophrenia spectrum disorders (TEOSS): demographic and clinical characteristics.
Jean A. Frazier,Jon McClellan,Robert L. Findling,Benedetto Vitiello,Robert H. Anderson,Benjamin Zablotsky,Emily A. Williams,Nora K. McNamara,Joseph A. Jackson,Louise Ritz,Stefanie A. Hlastala,Leslie Pierson,Jennifer A. Varley,Madeline Puglia,Ann E. Maloney,Denisse Ambler,Tyehimba Hunt-Harrison,Robert M. Hamer,Nancy Noyes,Jeffrey A. Lieberman,Linmarie Sikich +20 more
TL;DR: A comparison to published reports of adults with SZ indicates that these youths may have more severe symptoms based on results of the Positive and Negative Symptom Scale, and the symptom profiles are consistent with, but more severe than, those reported in the adult literature.
Journal ArticleDOI
Double-Blind Maintenance Safety and Effectiveness Findings From the Treatment of Early-Onset Schizophrenia Spectrum (TEOSS) Study
Robert L. Findling,Jacqueline L. Johnson,Jon McClellan,Jean A. Frazier,Jean A. Frazier,Benedetto Vitiello,Robert M. Hamer,Jeffrey A. Lieberman,Jeffrey A. Lieberman,Louise Ritz,Nora K. McNamara,Jacqui Lingler,Stefanie A. Hlastala,Leslie Pierson,Madeline Puglia,Ann E. Maloney,Ann E. Maloney,Emily Michael Kaufman,Emily Michael Kaufman,Nancy Noyes,Nancy Noyes,Linmarie Sikich +21 more
TL;DR: No agent demonstrated superior efficacy, and all were associated with side effects, including weight gain, while improved treatments are needed for early-onset schizophrenia spectrum disorders.