D
Dennis Drayna
Researcher at National Institutes of Health
Publications - 48
Citations - 8835
Dennis Drayna is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Locus (genetics) & Gene. The author has an hindex of 29, co-authored 46 publications receiving 8486 citations. Previous affiliations of Dennis Drayna include Genentech & Howard Hughes Medical Institute.
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Human lecithin-cholesterol acyltransferase gene: complete gene sequence and sites of expression
TL;DR: Blot hybridization data suggest that there is only one LCAT gene in humans, and the 1550 base LCAT mRNA can be detected in liver and HepG2 cells, but not in small intestine, spleen, pancreas, placenta or adrenal tissue.
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Multiple RFLPs at the human cholesteryl ester transfer protein (CETP) locus.
Dennis Drayna,Richard M. Lawn +1 more
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Genetic linkage between lipoprotein(a) phenotype and a DNA polymorphism in the plasminogen gene.
Dennis Drayna,Robert A. Hegele,Philip E. Hass,Mitsuru Emi,Lily Wu,Dan L. Eaton,Richard M. Lawn,Roger R. Williams,Ray White,Jean-Marc Lalouel +9 more
TL;DR: Free recombination between the same phenotype and alleles of the apoB DNA polymorphism is found, which suggests that apo(a) size isoforms and plasma lipoprotein( a) concentrations are each determined by genetic variation at the aposminogen locus.
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Associations Between Phenylthiocarbamide Gene Polymorphisms and Cigarette Smoking
Dale S. Cannon,Timothy B. Baker,Megan E. Piper,Mary Beth Scholand,Daniel L. Lawrence,Dennis Drayna,William M. McMahon,G. Martin Villegas,Trace C. Caton,Hilary Coon,Mark Leppert +10 more
TL;DR: The results did not support the predicted association between the PAV and AVI haplotypes and smoker odds, but the AAV haplotype, which confers intermediate PTC/PROP taste sensitivity, was associated with reduced smoker prevalence.
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Results of a genome-wide linkage scan for stuttering.
Yin Yao Shugart,Jennifer Mundorff,James Kilshaw,Kimberly F. Doheny,Betty Q. Doan,Jacqueline Wanyee,Eric D. Green,Dennis Drayna +7 more
TL;DR: The results suggest chromosome 18 may harbor a predisposing locus for this disorder, and additional genes may exist.