M
Mitsuru Emi
Researcher at University of Hawaii
Publications - 284
Citations - 12314
Mitsuru Emi is an academic researcher from University of Hawaii. The author has contributed to research in topics: Gene & Loss of heterozygosity. The author has an hindex of 62, co-authored 282 publications receiving 11874 citations. Previous affiliations of Mitsuru Emi include Hyogo College of Medicine & Nippon Medical School.
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Journal Article
Homozygous Deletion and Frequent Allelic Loss of Chromosome 8p22 Loci in Human Prostate Cancer
G S Bova,Bob S. Carter,Bob S. Carter,Bob S. Carter,M J Bussemakers,Mitsuru Emi,Y Fujiwara,Natasha Kyprianou,S C Jacobs,John C. Robinson,Jonathan I. Epstein,Patrick C. Walsh +11 more
TL;DR: A common region of loss of heterozygosity at 8p22 and a homozygous deletion of the MSR locus contained within this region are defined, suggesting the presence of a tumor suppressor gene in this region which is frequently inactivated in prostate cancer.
Journal ArticleDOI
Genotyping and sequence analysis of apolipoprotein E isoforms
Mitsuru Emi,Lily Wu,Margaret Robertson,Richard L. Myers,Robert A. Hegele,Roger R. Williams,Ray White,Jean-Marc Lalouel +7 more
TL;DR: A genotypic method based on hybridization of allele-specific oligonucleotides with enzymatically amplified genomic DNA permits unambiguous diagnosis of six common apoE phenotypes within 24 h and finds two rare structural mutants of apo E2 in addition to the common E2 form.
Journal Article
Frequent Loss of Heterozygosity for Loci on Chromosome 8p in Hepatocellular Carcinoma, Colorectal Cancer, and Lung Cancer
Mitsuru Emi,Yoshiyuki Fujiwara,Toshifusa Nakajima,Eiju Tsuchiya,Hitoshi Tsuda,Setsuo Hirohashi,Yoshiharu Maeda,Kouji Tsuruta,Michiko Miyaki,Yusuke Nakamura +9 more
TL;DR: Analysis of paired tumor and constitutional DNA from 346 patients representing seven different types of human cancer suggested that one or more tumor suppressor genes for both cancers may be present in that region of chromosome 8p, 8p23.
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High Incidence of Somatic BAP1 alterations in sporadic malignant mesothelioma.
Masaki Nasu,Mitsuru Emi,Sandra Pastorino,Mika Tanji,Amy Powers,Hugh Luk,Francine Baumann,Yu An Zhang,Adi F. Gazdar,Shreya Kanodia,Maarit Tiirikainen,Erin G. Flores,Giovanni Gaudino,Michael J. Becich,Harvey I. Pass,Haining Yang,Michele Carbone +16 more
TL;DR: The findings conclusively establish BAP1 as the most commonly mutated gene in MM, regardless of ethnic background or other clinical characteristics, according to genomic and immunohistochemical analyses.
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Association of estrogen receptor dinucleotide repeat polymorphism with osteoporosis.
Michio Sano,Satoshi Inoue,Takayuki Hosoi,Yasuyoshi Ouchi,Mitsuru Emi,Masataka Shiraki,Hajime Orimo +6 more
TL;DR: The results suggest that genetic variation at the ER locus may be associated with some determinants for BMD and bone metabolism in postmenopausal women.