Dharsan Soundarrajan

TL;DR: Interestingly, 2k Da PEG-modifed SPIONs displayed the lowest cellular uptake and cytotoxicity among all studied particles, emphasizing the importance of surface coatings when engineering nanoparticles for biomedical applications.

TL;DR: This work designed a quantitative image-analysis pipeline for decoding organ-level calcium signaling, and extracted spatiotemporal features of calcium signaling dynamics during the development of the Drosophila larval wing disc, a genetic model for organogenesis.

TL;DR: This short review highlights a selective set of studies that have investigated the roles of physiological signaling in modulating and mediating morphogen‐based pattern formation and concludes that mounting evidence demonstrates that physiological signaling plays a role in ensuring robustness of morphogen-based signaling.

TL;DR: A generalized multicellular model of Ca2+ is developed that captures all the key categories ofCa2+ activity as a function of key hormonal signals and reveals that a “goldilocks zone” of optimal Ca2+.

TL;DR: In this article, the authors used a combination of computational modeling and experimental approaches to identify two different populations of cells within tissues that are connected by gap junction proteins, termed as initiator cells and standby cells.