D
Diane M. Simeone
Researcher at University of Michigan
Publications - 297
Citations - 23025
Diane M. Simeone is an academic researcher from University of Michigan. The author has contributed to research in topics: Pancreatic cancer & Cancer. The author has an hindex of 66, co-authored 261 publications receiving 20569 citations. Previous affiliations of Diane M. Simeone include New York University & University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
Ultra‐Specific Isolation of Circulating Tumor Cells Enables Rare‐Cell RNA Profiling
Rhonda M. Jack,Meggie M. G. Grafton,Danika Rodrigues,María Dolores Giráldez,Catherine Griffith,Robert Cieslak,Mina Zeinali,Chandan Kumar Sinha,Ebrahim Azizi,Max S. Wicha,Muneesh Tewari,Diane M. Simeone,Sunitha Nagrath +12 more
TL;DR: What is described herein is the ultra‐pure isolation of CTCs from patient blood samples and how this platform has enabled highly specific molecular (mRNA and miRNA) profiling of patient C TCs.
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Spectral areas and ratios classifier algorithm for pancreatic tissue classification using optical spectroscopy.
Malavika Chandra,James M. Scheiman,Diane M. Simeone,Barbara J. McKenna,Julianne Purdy,Mary Ann Mycek +5 more
TL;DR: The first assessment of the diagnostic accuracy of algorithms developed for pancreatic tissue classification using data from fiber optic probe-based bimodal optical spectroscopy is presented, a real-time approach that would be compatible with minimally invasive diagnostic procedures for early cancer detection in the pancreas.
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Microfluidic continuum sorting of sub-populations of tumor cells via surface antibody expression levels
Rhonda M. Jack,Khadijah Hussain,Danika Rodrigues,Mina Zeinali,Mina Zeinali,Ebrahim Azizi,Max S. Wicha,Diane M. Simeone,Sunitha Nagrath +8 more
TL;DR: A robust method of isolating pancreatic cancer CTCs according to their varying protein levels is demonstrated, which enables extensive studies on tumor cell heterogeneity, and may yield therapeutic targets against virulent cell subpopulations.
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Clinical evaluation, imaging studies, indications for cytologic study, and preprocedural requirements for duct brushing studies and pancreatic FNA: The papanicolaou society of cytopathology recommendations for pancreatic and biliary cytology
Douglas G. Adler,C. Max Schmidt,Mohammad A. Al-Haddad,James S. Barthel,Britt-Marie Ljung,Nipun B. Merchant,Joseph Romagnuolo,Akram M. Shaaban,Diane M. Simeone,Martha B. Pitman,Andrew S. Field,Lester J. Layfield +11 more
TL;DR: This document selectively presents the results of discussions on indications for endoscopic ultrasound and fine‐needle aspiration biopsy, techniques for EUS‐FNA, terminology and nomenclature to be used for pancreaticobiliary disease, ancillary testing, and post‐biopsy management.
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Characterizing human pancreatic cancer precursor using quantitative tissue optical spectroscopy.
Seung Yup Lee,William R. Lloyd,Malavika Chandra,Robert H. Wilson,Barbara J. McKenna,Diane M. Simeone,James M. Scheiman,Mary Ann Mycek +7 more
TL;DR: The results suggest that tissue optical spectroscopy has the potential to characterize pre-cancerous neoplasms in human pancreatic tissues.