D
Dick Hoekstra
Researcher at University Medical Center Groningen
Publications - 280
Citations - 19674
Dick Hoekstra is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Vesicle & Lipid bilayer fusion. The author has an hindex of 69, co-authored 280 publications receiving 18789 citations. Previous affiliations of Dick Hoekstra include University of Groningen.
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Translocation of fluorescent ether phospholipid, but not its diacyl counterpart, after insertion in plasma membranes of control and plasmalogen-deficient fibroblasts
TL;DR: Analysis by thin-layer chromatography reveals that the translocation involves transfer of the intact ether phosphatidylcholine molecules, which differs markedly from that of its diacyl phospholipid analogue, which remains associated with the plasma membrane under similar conditions.
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Long term myriocin treatment increases MRP1 transport activity
Peter Meszaros,Karin Klappe,Annie van Dam,Pavlina T. Ivanova,Stephen B. Milne,David S. Myers,H. Alex Brown,Hjalmar P. Permentier,Dick Hoekstra,Jan Willem Kok +9 more
TL;DR: It is demonstrated that the effect of myriocin treatment on multidrug resistance-related protein 1 (MRP1) efflux activity in MRP1 expressing cells and isolated plasma membrane vesicles is due to an enhanced recruitment of MRp1 into lipid raft fractions, thereby promoting MRP 1 activity.
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The toolbox of vesicle sidedness determination
TL;DR: The ins and outs of sidedness determination of vesicles is focused on and various methodologies used to establish this ratio are compared.