D
Dick Hoekstra
Researcher at University Medical Center Groningen
Publications - 280
Citations - 19674
Dick Hoekstra is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Vesicle & Lipid bilayer fusion. The author has an hindex of 69, co-authored 280 publications receiving 18789 citations. Previous affiliations of Dick Hoekstra include University of Groningen.
Papers
More filters
Journal ArticleDOI
[18F]FDG labeling of neural stem cells for in vivo cell tracking with positron emission tomography: inhibition of tracer release by phloretin
Katica Stojanov,Erik F. J. de Vries,Dick Hoekstra,Aren van Waarde,Rudi Dierckx,Inge S. Zuhorn +5 more
TL;DR: 2′-[18F]fluoro-2′-deoxy-D-glucose ([18F]-FDG, a PET tracer, is found to be a poor radiopharmaceutical to label NSCs owing to the low labeling efficiency and substantial release of radioactivity from these cells.
Journal ArticleDOI
Metabolism and apoptotic properties of elevated ceramide in ht29rev cells
TL;DR: The inability of bSMase to induce apoptosis of HT29(rev) cells does not appear to be due to rapid metabolic conversion of excessive Cer, and it is proposed that the intracellular target involved in the propagation of the apoptotic signal is reached by C2-Cer, but not by b SMase-generated Cer.
Journal ArticleDOI
Lipid trafficking and sorting: how cholesterol is filling gaps
TL;DR: A role for cholesterol homeostasis in the regulation of trafficking and sorting of sphingolipids may dictate the nature of the acyl chain species of phospholipid in the plasma membrane which may govern the selective partitioning of these lipids into lateral domains.
Journal ArticleDOI
Fibronectin attenuates process outgrowth in oligodendrocytes by mislocalizing MMP-9 activity
TL;DR: It is suggested that ECM molecules influence both the net activity of secreted MMP and the spatial distribution of cell-associated MMP activity, and thereby morphological oligodendrocyte differentiation.
Journal ArticleDOI
PDMP blocks brefeldin A-induced retrograde membrane transport from Golgi to ER: evidence for involvement of calcium homeostasis and dissociation from sphingolipid metabolism.
Jan Willem Kok,Teresa Babia,Catalin M. Filipeanu,Adriaan Nelemans,Gustavo Egea,Dick Hoekstra +5 more
TL;DR: The biological effects of PDMP revealed a relation between three important physiological processes of multidrug resistance, calcium homeostasis, and membrane flow in the ER/ Golgi system.