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Diego A. Golombek

Researcher at National University of Quilmes

Publications -  186
Citations -  6555

Diego A. Golombek is an academic researcher from National University of Quilmes. The author has contributed to research in topics: Circadian rhythm & Circadian clock. The author has an hindex of 40, co-authored 177 publications receiving 5725 citations. Previous affiliations of Diego A. Golombek include University of Buenos Aires & Facultad de Ciencias Exactas y Naturales.

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Physiology of circadian entrainment.

TL;DR: Several aspects of the mechanisms for photic entrainment of mammalian circadian rhythms are covered, including retinal sensitivity to light by means of novel photopigments as well as circadian variations in the retina that contribute to the regulation of retinal physiology.
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Crosstalk between the circadian clock circuitry and the immune system.

TL;DR: The circadian-immune connection is bidirectional, because in addition to this circadian control of immune functions, immune challenges and immune mediators were shown to have strong effects on circadian rhythms at the molecular, cellular, and behavioral levels.
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Melatonin effects on behavior: possible mediation by the central GABAergic system.

TL;DR: The effects of melatonin in rodent behavior are described, focusing on inhibitory effects (sedation, hypnotic activity, pain perception threshold elevation), and direct effects on circadian rhythmicity (entrainment, resynchronization, alleviation of jet-lag symptoms, phase-shifting).
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Circadian and Sleep Disorders in Parkinson’s Disease

TL;DR: The role of dopamine in regulation of sleep and alertness is reviewed and main sleep and circadian disturbances associated with PD are discussed and increasing body of evidence suggests that the circadian system becomes dysregulated in PD, which may lead to poor sleep and Alertness.
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Effects of lockdown on human sleep and chronotype during the COVID-19 pandemic.

TL;DR: It is shown that participants slept longer and later during lockdown weekdays, and exhibited lower levels of social jetlag, which may seem to be an overall improvement of sleep conditions.